SCHEMBL8459173

SCHEMBL8459173

CCCCCc1c(C(=O)O)cccc1N(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 5/20 0.44
KAT8 Q9H7Z6 4/20 0.43
BID P55957 3/20 0.43
MCL1 Q07820 3/20 0.43
PPARA Q07869 3/20 0.43
BCL2L1 Q07817 2/20 0.43
BAK1 Q16611 2/20 0.43
TSHR P16473 2/20 0.43
PPARG P37231 2/20 0.43
ALDH1A1 P00352 1/20 0.43
TP53 P04637 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
EP300 Q09472 1/20 0.43
KAT2A Q92830 1/20 0.43
KAT2B Q92831 1/20 0.43
KAT5 Q92993 1/20 0.43
SAE1 Q9UBE0 1/20 0.43
RARB P10826 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4592292 0.98 PLK1 (0.46) PLK1KAT8BIDMCL1PPARA
SCHEMBL11097739 0.92 ALDH1A1 (0.47) PLK1BIDMCL1BCL2L1BAK1
SCHEMBL27297604 0.87 PLK1 (0.50) PLK1KAT8BIDMCL1PPARA
SCHEMBL28103139 0.85 KAT8 (0.53) PLK1KAT8BIDMCL1PPARA
SCHEMBL27944047 0.85 KAT8 (0.53) PLK1KAT8BIDMCL1PPARA
SCHEMBL8757448 0.85 KAT8 (0.53) PLK1KAT8BIDMCL1PPARA
SCHEMBL27924691 0.85 KAT8 (0.53) PLK1KAT8BIDMCL1PPARA
SCHEMBL14836221 0.85 KAT8 (0.53) PLK1KAT8BIDMCL1PPARA
SCHEMBL27944035 0.85 KAT8 (0.53) PLK1KAT8BIDMCL1PPARA
SCHEMBL27924694 0.85 KAT8 (0.53) PLK1KAT8BIDMCL1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711801-B1 Method of indicating a cure point for ultraviolet radiation curing compositions by color change DOW CORNING (US) 1999-10-06 EP disclosed
EP-0711801-A2 Method of indicating a cure point for ultraviolet radiation curing compositions by color change DOW CORNING CORPORATION (US) 1996-05-15 EP disclosed
EP-0711802-A2 Method of indicating a cure point for ultraviolet radiation curing compositions by color change DOW CORNING CORPORATION (US) 1996-05-15 EP disclosed
EP-0456346-B1 Silicone organic conformal coatings DOW CORNING (US) 1994-10-12 EP disclosed
US-5302627-A For polysiloxanes DOW CORNING CORPORATION (US) 1994-04-12 US disclosed
EP-0456346-A2 Silicone organic conformal coatings DOW CORNING CORPORATION (US) 1991-11-13 EP disclosed
EP-0437247-A2 UV curable silicone resin-organic mercaptan composition DOW CORNING CORPORATION (US) 1991-07-17 EP disclosed