SCHEMBL8459185

SCHEMBL8459185

CCCCCCc1ccc(C2CCc3c(cc(F)c(OCCCCCCCC(C)CC)c3F)C2=O)nc1F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 5/20 0.31
CNR1 P21554 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7922694 0.83 CNR2 (0.31) CNR2CNR1
SCHEMBL7792752 0.83
SCHEMBL8461690 0.80 MAPT (0.34) CNR2CNR1
SCHEMBL7559498 0.75 CNR2 (0.33) CNR2CNR1
SCHEMBL7920153 0.73 GCGR (0.31) CNR2
SCHEMBL8462721 0.71 SPHK1 (0.33)
SCHEMBL8459168 0.65 TYR (0.36) CNR2CNR1
SCHEMBL8459322 0.64 CRBN (0.47)
SCHEMBL9874783 0.63 CNR2 (0.46) CNR2CNR1
SCHEMBL7932528 0.61 CYP3A4 (0.34) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0944570-A1 5,7-DIFLUORO-3,4-DIHYDRO-2H-NAPHTHALENE-1-ONE DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTAL MIXTURES Aventis Research & Technologies GmbH & Co. KG (DE) 1999-09-29 EP disclosed
WO-1998027045-A1 5,7-DIFLUORO-3,4-DIHYDRO-2H-NAPHTHALENE-1-ONE DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTAL MIXTURES AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) 1998-06-25 WO disclosed