Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.30 |
| ▸ | FEN1 | P39748 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920153 | 0.87 | GCGR (0.31) | CNR2 | |
| SCHEMBL7557099 | 0.78 | TYR (0.42) | CNR2CNR1FEN1MEN1TP53 | |
| SCHEMBL8459185 | 0.75 | CNR2 (0.31) | CNR2CNR1 | |
| SCHEMBL7792752 | 0.75 | — | — | |
| SCHEMBL7922694 | 0.73 | CNR2 (0.31) | CNR2CNR1 | |
| SCHEMBL8420829 | 0.71 | MEN1 (0.33) | CNR2MEN1TP53CYP3A4ALOX5 | |
| SCHEMBL9874783 | 0.67 | CNR2 (0.46) | CNR2CNR1CYP3A4 | |
| SCHEMBL7558787 | 0.66 | RARB (0.42) | MEN1MAPTTSHRKMT2A | |
| SCHEMBL7110595 | 0.65 | KDM4E (0.51) | CNR2CYP3A4MAPTHTT | |
| SCHEMBL6863866 | 0.65 | KDM4E (0.51) | CNR2CYP3A4MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944565-B1 | 1,3,5-TRIFLUORONAPHTHALENE DERIVATIVES FOR LIQUID CRYSTALLINE MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2002-07-31 | — | — | EP | disclosed |
| EP-0944565-A1 | 1,3,5-TRIFLUORONAPHTHALENE DERIVATIVES FOR LIQUID CRYSTALLINE MIXTURES | Aventis Research & Technologies GmbH & Co. KG (DE) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998027038-A1 | 1,3,5-TRIFLUORONAPHTHALENE DERIVATIVES FOR LIQUID CRYSTALLINE MIXTURES | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1998-06-25 | — | — | WO | disclosed |