Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459389 | 1.00 | MAPT (0.35) | MAPTABCC4ALDH1A1LMNAUSP2 | |
| SCHEMBL8458200 | 0.83 | PPARG (0.32) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8458198 | 0.83 | PPARG (0.32) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8960074 | 0.81 | — | — | |
| SCHEMBL10696540 | 0.80 | — | — | |
| SCHEMBL26728697 | 0.78 | MAPT (0.38) | MAPTABCC4ALDH1A1LMNAUSP2 | |
| SCHEMBL28606494 | 0.77 | ALDH1A1 (0.35) | ALDH1A1TSHRCYP2D6ALOX15 | |
| SCHEMBL9113394 | 0.77 | ALDH1A1 (0.35) | ALDH1A1TSHRCYP2D6ALOX15 | |
| SCHEMBL1509789 | 0.77 | ALDH1A1 (0.35) | ALDH1A1TSHRCYP2D6ALOX15 | |
| SCHEMBL296964 | 0.77 | MAPT (0.46) | MAPTABCC4ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5961483-A | Iontophoretic delivery of cell adhesion inhibitors | COLLATERAL AGENTS, LLC | 1999-10-05 | — | — | US | disclosed |
| US-5935598-A | DEVICE FOR NON-INVASIVE ADMINISTRATION OF A CELL ADHESION RECEPTOR ANTAGONIST TO A MAMMAL; CURRENT DISTRIBUTING MEMBER, IONIZABLE ANTAGONIST RESERVOIR, ELECTROLYTE RESERVOIR, POWDER SOURCE; TREATING THROMBOSIS, ANTICOAGULANTS | BECTON DICKINSON RESEARCH CENTER (US) | 1999-08-10 | — | — | US | disclosed |
| US-5849736-A | Isoxazoline and isoxazole fibrinogen receptor antagonists | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-12-15 | — | — | US | disclosed |