SCHEMBL8459396

SCHEMBL8459396

CCCCOC(CCC[SiH3])OCCCC

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
SMPD1 P17405 3/20 0.31
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8458935 0.88
SCHEMBL8462439 0.88 ADRB2 (0.35) DNM1ADRB2ADRB1ADRB3CA1
SCHEMBL9759984 0.85 ADRB2 (0.39) DNM1ADRB2ADRB1ADRB3CA1
SCHEMBL7531962 0.85 ADRB2 (0.39) DNM1ADRB2ADRB1ADRB3CA1
SCHEMBL31636211 0.85 SMPD1 (0.40) DNM1ADRB2ADRB1ADRB3CA1
SCHEMBL1897872 0.83 SMPD1 (0.43) DNM1ADRB2ADRB1ADRB3CA1
SCHEMBL9809153 0.81 SMPD1 (0.47) DNM1CA1CA2SMPD1TSHR
SCHEMBL14780190 0.81 SMPD1 (0.47) DNM1CA1CA2SMPD1TSHR
SCHEMBL14778871 0.81 SMPD1 (0.47) DNM1CA1CA2SMPD1TSHR
SCHEMBL14779185 0.81 SMPD1 (0.47) DNM1CA1CA2SMPD1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0604677-B1 Method of making coated shaped articles MITSUBISHI RAYON CO (JP) 1999-08-11 EP disclosed
US-5470616-A Coated shaped articles and method of making same MITSUBISHI RAYON CO., LTD. (JP) 1995-11-28 US disclosed
EP-0604677-A1 Coated shaped articles and method of making same MITSUBISHI RAYON CO., LTD. (JP) 1994-07-06 EP disclosed