Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 4/20 | 0.35 |
| ▸ | HRH1 | P35367 | 4/20 | 0.35 |
| ▸ | REN | P00797 | 3/20 | 0.35 |
| ▸ | RORC | P51449 | 8/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582658 | 1.00 | HRH2 (0.35) | HRH2HRH1RENRORCCACNA1B | |
| SCHEMBL4582662 | 1.00 | HRH2 (0.35) | HRH2HRH1RENRORCCACNA1B | |
| SCHEMBL4583243 | 0.94 | REN (0.36) | HRH2HRH1RENRORC | |
| SCHEMBL4583244 | 0.94 | REN (0.36) | HRH2HRH1RENRORC | |
| SCHEMBL4582750 | 0.93 | REN (0.36) | HRH2HRH1RENRORC | |
| SCHEMBL4582751 | 0.93 | REN (0.36) | HRH2HRH1RENRORC | |
| SCHEMBL4583360 | 0.92 | REN (0.35) | RENRORC | |
| SCHEMBL4583363 | 0.92 | REN (0.35) | RENRORC | |
| SCHEMBL4584012 | 0.91 | REN (0.36) | HRH2HRH1RENRORC | |
| SCHEMBL4584015 | 0.91 | REN (0.36) | HRH2HRH1RENRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908762-A2 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |