Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3625681 | 1.00 | TSHR (0.67) | TSHRALDH1A1TDP1SMN1; SMN2LPAR3 | |
| SCHEMBL3619125 | 1.00 | TSHR (0.67) | TSHRALDH1A1TDP1SMN1; SMN2LPAR3 | |
| SCHEMBL21678801 | 1.00 | TSHR (0.67) | TSHRALDH1A1TDP1SMN1; SMN2LPAR3 | |
| SCHEMBL21678806 | 1.00 | TSHR (0.67) | TSHRALDH1A1TDP1SMN1; SMN2LPAR3 | |
| SCHEMBL3620335 | 0.98 | TSHR (0.69) | TSHRALDH1A1TDP1SMN1; SMN2LPAR3 | |
| SCHEMBL823835 | 0.96 | TSHR (0.62) | TSHRALDH1A1TDP1SMN1; SMN2LPAR3 | |
| SCHEMBL2734737 | 0.92 | TSHR (0.65) | TSHRALDH1A1TDP1SMN1; SMN2LPAR3 | |
| SCHEMBL29193682 | 0.88 | ALDH1A1 (0.63) | TSHRALDH1A1TDP1SMN1; SMN2LPAR3 | |
| SCHEMBL30736012 | 0.86 | TSHR (0.49) | TSHRALDH1A1TDP1SMN1; SMN2LPAR3 | |
| SCHEMBL7109410 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691327-B1 | AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME | KAO CORP (JP) | 1999-07-21 | — | — | EP | disclosed |
| US-5723497-A | AMINE ALCOHOL DERIVATIVES FOR WRINKLE RESISTNCE | KAO CORPORATION (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0691327-A1 | AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME | Kao Corporation (JP) | 1996-01-10 | — | — | EP | disclosed |