Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 19/20 | 0.54 |
| ▸ | HTR1D | P28221 | 10/20 | 0.50 |
| ▸ | HTR1B | P28222 | 9/20 | 0.47 |
| ▸ | HTR1A | P08908 | 8/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR1E | P28566 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013501 | 0.80 | HTR1F (0.65) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7013905 | 0.75 | HTR1F (0.70) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7013589 | 0.74 | HTR1F (0.80) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8458326 | 0.73 | HTR1F (0.68) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7012060 | 0.73 | HTR1F (0.79) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7015495 | 0.73 | HTR1F (0.72) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7012407 | 0.73 | HTR1F (0.54) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL30909195 | 0.72 | HTR1F (0.55) | HTR1FHTR1DHTR1B | |
| Toluic Acid SCHEMBL7013141 | 0.71 | HTR1F (0.56) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7475547 | 0.71 | HTR1D (0.56) | HTR1FHTR1DHTR1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919936-A | 5-HT1F AGONIST INTERMEDIATES | ELI LILLY AND COMPANY (US) | 1999-07-06 | — | — | US | disclosed |