Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 4/20 | 0.55 |
| ▸ | RARB | P10826 | 4/20 | 0.55 |
| ▸ | RARG | P13631 | 4/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.49 |
| ▸ | GOT1 | P17174 | 1/20 | 0.49 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9189893 | 1.00 | RARA (0.55) | RARARARBRARGHDAC11HDAC2 | |
| SCHEMBL9186030 | 0.91 | RARA (0.67) | RARARARBRARGHDAC11HDAC2 | |
| SCHEMBL9187408 | 0.91 | RARA (0.67) | RARARARBRARGHDAC11HDAC2 | |
| SCHEMBL8459692 | 0.88 | RARA (0.49) | RARARARBRARGHDAC11HDAC2 | |
| SCHEMBL9191306 | 0.83 | RARA (0.55) | RARARARBRARGHDAC11HDAC2 | |
| SCHEMBL566278 | 0.82 | RARA (0.62) | RARARARBRARGHDAC11HDAC2 | |
| SCHEMBL9079300 | 0.81 | RARB (0.82) | RARARARBRARGHDAC11HDAC2 | |
| SCHEMBL9079305 | 0.81 | RARB (0.82) | RARARARBRARGHDAC11HDAC2 | |
| SCHEMBL25200687 | 0.80 | RARB (0.69) | RARARARBRARGHDAC11HDAC2 | |
| SCHEMBL8459229 | 0.79 | RARA (0.55) | RARARARBRARGHDAC11HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869067-A | TREATING DERMATOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1999-02-09 | — | — | US | claimed |
| EP-0514269-B1 | Imino-derivatives, process for their preparation and their use in human and veterinary medicine and in cosmetics | CIRD GALDERMA (FR) | 1995-11-02 | — | — | EP | claimed |
| US-5869067-A | TREATING DERMATOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1999-02-09 | — | — | US | disclosed |
| US-5753239-A | Bi-aromatic compounds and pharmaceutical and cosmetic compositions | CENTRE INTERNATIONAL DE RECHERCHES DEMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1998-05-19 | — | — | US | disclosed |