Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.57 |
| ▸ | APP | P05067 | 4/20 | 0.57 |
| ▸ | SNCA | P37840 | 4/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.51 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.51 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | RXRA | P19793 | 5/20 | 0.48 |
| ▸ | RARA | P10276 | 5/20 | 0.48 |
| ▸ | RARB | P10826 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8462052 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CYP3A4APPSNCAALOX15 | |
| SCHEMBL8458864 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CYP3A4APPSNCAALOX15 | |
| SCHEMBL19652484 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CYP3A4APPSNCAALOX15 | |
| SCHEMBL8950124 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CYP3A4APPSNCAALOX15 | |
| SCHEMBL19652488 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CYP3A4APPSNCAALOX15 | |
| SCHEMBL8776535 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CYP3A4APPSNCAALOX15 | |
| SCHEMBL8950189 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CYP3A4APPSNCAALOX15 | |
| SCHEMBL9117657 | 0.93 | ALDH1A1 (0.60) | ALDH1A1CYP3A4APPSNCAALOX15 | |
| SCHEMBL7694175 | 0.93 | ALDH1A1 (0.60) | ALDH1A1CYP3A4APPSNCAALOX15 | |
| SCHEMBL21959207 | 0.85 | ALDH1A1 (0.50) | ALDH1A1CYP3A4APPSNCAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999048529-A1 | RETINOID-GLITAZONE COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 1999-09-30 | — | — | WO | disclosed |
| US-5489611-A | ADMINISTERING A RETINOID COMPOUND | WARNER-LAMBERT COMPANY (US) | 1996-02-06 | — | — | US | disclosed |