SCHEMBL8460697

SCHEMBL8460697

C=COCCCCc1ccc(Cl)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 1/20 0.44
ALOX15 P16050 1/20 0.44
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
TAAR1 Q96RJ0 2/20 0.41
KCNH2 Q12809 5/20 0.40
SLC6A2 P23975 2/20 0.40
HRH1 P35367 2/20 0.40
HRH3 Q9Y5N1 2/20 0.40
CHRM2 P08172 1/20 0.40
ADRA2C P18825 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8461107 0.81 TAAR1 (0.41) TAAR1SCN5AGAAMAOB
SCHEMBL14142736 0.81 ALDH1A1 (0.41) MAOB
SCHEMBL7590883 0.81 IDO1 (0.48) SIGMAR1MAOB
SCHEMBL14142751 0.80 ALDH1A1 (0.39) SLC6A2CHRM2ADRA2CSLC6A4SLC6A3
SCHEMBL11959867 0.79 IGF1R (0.48) IGF1RALOX15HDAC3HDAC4HDAC1
SCHEMBL12691976 0.79 HRH3 (0.36) HRH3MAOB
SCHEMBL11959919 0.77 KCNH2 (0.49) IGF1RALOX15HDAC3HDAC4HDAC1
SCHEMBL10365734 0.77 IGF1R (0.64) IGF1RALOX15HDAC3HDAC4HDAC1
SCHEMBL6905786 0.76 KCNH2 (0.56) IGF1RALOX15HDAC3HDAC4HDAC1
SCHEMBL8942993 0.76 KCNH2 (0.47) IGF1RALOX15HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5891964-A A TETRAFLUOROETHYLENE/PERFLUORO(LOWER ALKYL VINYL ETHER) OR -(LOWER ALKOXY VINYL ETHER)/HALOGENOPHENYL-CONTAINING VINYL ETHER POLYMER; VULCANIZATION, E.G. BISPHENOL AF NIPPON MEKTRON, LIMITED (JP) 1999-04-06 US disclosed