Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.48 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8460717 | 1.00 | MAPT (0.48) | MAPTMEN1KMT2APLIN1LMNA | |
| SCHEMBL8835428 | 0.85 | HIF1A (0.48) | MAPTMEN1KMT2ALMNATSHR | |
| SCHEMBL7209021 | 0.85 | HIF1A (0.48) | MAPTMEN1KMT2ALMNATSHR | |
| SCHEMBL7206001 | 0.85 | HIF1A (0.48) | MAPTMEN1KMT2ALMNATSHR | |
| SCHEMBL8435835 | 0.82 | TSHR (0.47) | MAPTMEN1KMT2APLIN1LMNA | |
| SCHEMBL8435839 | 0.82 | TSHR (0.47) | MAPTMEN1KMT2APLIN1LMNA | |
| SCHEMBL8613981 | 0.78 | HIF1A (0.53) | MAPTMEN1KMT2APLIN1LMNA | |
| SCHEMBL3625146 | 0.78 | HIF1A (0.47) | MAPTMEN1KMT2APLIN1LMNA | |
| SCHEMBL7773929 | 0.78 | HIF1A (0.47) | MAPTMEN1KMT2APLIN1LMNA | |
| SCHEMBL8613983 | 0.78 | HIF1A (0.53) | MAPTMEN1KMT2APLIN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949243-A1 | OPTICALLY ACTIVE METHOXYIMINOACETAMIDE DERIVATIVES, PROCESS FOR THE PREPARATION OF THEM, INTERMEDIATES THEREFOR, AND PESTICIDES CONTAINING THEM AS THE ACTIVE INGREDIENT | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-10-13 | — | — | EP | disclosed |
| EP-0838452-A1 | PROCESS FOR PRODUCING N-METHYL-METHOXYIMINOACETAMIDE DERIVATIVES AND INTERMEDIATES THEREOF | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-04-29 | — | — | EP | disclosed |