Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464724 | 0.80 | IDO1 (0.55) | GPR35GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL8460658 | 0.79 | CA1 (0.43) | GRIN2DGRIN2AGRIN2BGRIN2CCA1 | |
| SCHEMBL8460627 | 0.78 | HSD17B10 (0.40) | GPR35GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL8462678 | 0.75 | GRIN2D (0.68) | GPR35GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL5369132 | 0.75 | GRIN2D (0.57) | GRIN2DGRIN2AGRIN2BGRIN2CCA1 | |
| SCHEMBL5353853 | 0.75 | GRIN2D (0.57) | GRIN2DGRIN2AGRIN2BGRIN2CCA1 | |
| SCHEMBL204252 | 0.72 | GPR35 (0.46) | GPR35GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL8999881 | 0.72 | GPR35 (0.46) | GPR35GRIN2DGRIN2AGRIN2BGRIN2C | |
| Hydrochloric Acid SCHEMBL9860418 | 0.70 | GPR35 (0.45) | GPR35GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL29420745 | 0.69 | IDO1 (0.48) | GPR35GRIN2DGRIN2AGRIN2BGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |