Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809209 | 0.95 | TTR (0.34) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL5178712 | 0.95 | TTR (0.34) | TTRFABP4CCNA2CDK2MAPK14 | |
| Sulfurous Acid SCHEMBL8461551 | 0.94 | TTR (0.30) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL571228 | 0.88 | — | — | |
| SCHEMBL4871382 | 0.87 | SNCA (0.30) | — | |
| SCHEMBL15769083 | 0.86 | TTR (0.34) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL1537228 | 0.84 | SLC16A3 (0.34) | — | |
| SCHEMBL571230 | 0.83 | — | — | |
| SCHEMBL1276734 | 0.75 | PLAU (0.33) | — | |
| SCHEMBL28977868 | 0.75 | TTR (0.32) | TTRFABP4CCNA2CDK2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004731-A | GUANIDINE COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1999-12-21 | — | — | US | disclosed |