SCHEMBL15769083

SCHEMBL15769083

O=S(=O)(O)c1ccccc1/C=C/c1ccccc1Nc1ccnnn1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.34
FABP4 P15090 1/20 0.34
CCNA2 P20248 1/20 0.34
CDK2 P24941 1/20 0.34
MAPK14 Q16539 1/20 0.34
NR4A1 P22736 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PTGES2 Q9H7Z7 1/20 0.32
SNCA P37840 1/20 0.31
SLC16A3 O15427 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5178712 0.91 TTR (0.34) TTRFABP4CCNA2CDK2MAPK14
SCHEMBL3809209 0.91 TTR (0.34) TTRFABP4CCNA2CDK2MAPK14
SCHEMBL4871382 0.86 SNCA (0.30) SNCA
Sulfurous Acid SCHEMBL8461547 0.86 TTR (0.31) TTRFABP4CCNA2CDK2MAPK14
SCHEMBL571230 0.85
SCHEMBL1072234 0.85 MEN1 (0.36) SNCA
Sulfurous Acid SCHEMBL8461551 0.84 TTR (0.30) TTRFABP4CCNA2CDK2MAPK14
SCHEMBL571228 0.82
SCHEMBL1537228 0.79 SLC16A3 (0.34) SNCASLC16A3
SCHEMBL285342 0.79 TRPA1 (0.38) SNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140162083-A1 STILBENE-BASED REACTIVE COMPOUNDS, POLYMERIC MATRICES FORMED THEREFROM, AND ARTICLES VISUALIZABLE BY FLUORESCENCE SURMODICS, INC. (US) 2014-06-12 US claimed
US-9629945-B2 Stilbene-based reactive compounds, polymeric matrices formed therefrom, and articles visualizable by fluorescence SURMODICS, INC. (US) 2017-04-25 US disclosed
US-20140162083-A1 STILBENE-BASED REACTIVE COMPOUNDS, POLYMERIC MATRICES FORMED THEREFROM, AND ARTICLES VISUALIZABLE BY FLUORESCENCE SURMODICS, INC. (US) 2014-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140162083-A1 STILBENE-BASED REACTIVE COMPOUNDS, POLYMERIC MATRICES FORMED THEREFROM, AND ARTICLES VISUALIZABLE BY FLUORESCENCE ITK, NOTUM, ITGAM TTR 3411/4885FABP4 4635/4885CCNA2 1964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.