Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8463750 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL8462570 | 0.68 | — | — | |
| SCHEMBL630634 | 0.64 | HDAC6 (0.41) | DAOHDAC8HDAC6AURKAAURKB | |
| SCHEMBL1377973 | 0.63 | DAO (0.35) | DAOHDAC8HDAC6AURKAAURKB | |
| Hydrochloric Acid SCHEMBL7988951 | 0.61 | HDAC6 (0.40) | DAOHDAC8HDAC6AURKAAURKB | |
| Hydrochloric Acid SCHEMBL11060860 | 0.59 | — | — | |
| SCHEMBL211077 | 0.59 | — | — | |
| SCHEMBL47202 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL7134235 | 0.58 | — | — | |
| Hydrochloric Acid SCHEMBL8458248 | 0.58 | MCL1 (0.32) | DAOHDAC8HDAC6AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741145-B1 | Olefin polymerization catalyst and process for producing polyolefin using the same | SUMITOMO CHEMICAL CO (JP) | 1999-12-29 | — | — | EP | disclosed |
| EP-0741145-A1 | Olefin polymerization catalyst and process for producing polyolefin using the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-11-06 | — | — | EP | disclosed |