Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 7/20 | 0.72 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8465625 | 1.00 | LTB4R (0.72) | LTB4RALOX5APPDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL8462004 | 1.00 | LTB4R (0.72) | LTB4RALOX5APPDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL8465622 | 1.00 | LTB4R (0.72) | LTB4RALOX5APPDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL8466275 | 0.91 | LTB4R (0.58) | LTB4RALOX5APPDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL8462851 | 0.91 | LTB4R (0.58) | LTB4RALOX5APPDE10ACYSLTR1CYSLTR2 | |
| Hydrochloric Acid SCHEMBL8465772 | 0.90 | LTB4R (0.57) | LTB4RALOX5APPDE10ACYSLTR1CYSLTR2 | |
| Hydrochloric Acid SCHEMBL8465778 | 0.90 | LTB4R (0.57) | LTB4RALOX5APPDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL8890412 | 0.86 | LTB4R (0.53) | LTB4RALOX5APPDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL8466123 | 0.83 | LTB4R (1.00) | LTB4RALOX5APPDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL8466125 | 0.83 | LTB4R (1.00) | LTB4RALOX5APPDE10ACYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998451-A | LIPOXYGENASE INHIBITORS | PFIZER INC (US) | 1999-12-07 | — | — | US | disclosed |
| US-5059609-A | Lipoxygenase inhibitors; leukotriene receptor blockers; psoriasis; antiulcer agents and myocardial infarctions | PFIZER INC. (US) | 1991-10-22 | — | — | US | disclosed |