Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464878 | 0.74 | GAA (0.38) | GAAGABRA2GABRB2KDM4EALDH1A1 | |
| SCHEMBL8466902 | 0.74 | GAA (0.38) | GAAGABRA2GABRB2KDM4EALDH1A1 | |
| SCHEMBL9046316 | 0.70 | KDM4E (0.35) | KDM4EALDH1A1POLBHPGDCYP1A2 | |
| SCHEMBL16519359 | 0.68 | CYP1A2 (0.53) | GAAGABRA2GABRB2KDM4EALDH1A1 | |
| SCHEMBL5140534 | 0.67 | MITF (0.49) | GAAGABRA2GABRB2KDM4EALDH1A1 | |
| SCHEMBL1001660 | 0.66 | CYP1A2 (0.50) | GAAGABRA2GABRB2KDM4EALDH1A1 | |
| SCHEMBL25658525 | 0.66 | CYP1A2 (0.50) | GAAGABRA2GABRB2KDM4EALDH1A1 | |
| SCHEMBL16268836 | 0.66 | CYP1A2 (0.50) | GAAGABRA2GABRB2KDM4EALDH1A1 | |
| SCHEMBL26311965 | 0.66 | GAA (0.52) | GAAGABRA2GABRB2KDM4EALDH1A1 | |
| SCHEMBL5041765 | 0.64 | CYP1A2 (0.47) | GAAGABRA2GABRB2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912243-A | NOVEL COMPOUNDS FOR CONTROLLING NEMATODES, INSECT OR ACARID PESTS | ZENECA LIMITED (GB) | 1999-06-15 | — | — | US | disclosed |
| US-5705516-A | NEMATOCIDES, INSECTICIDES, ACARICIDES | ZENECA LIMITED (GB) | 1998-01-06 | — | — | US | disclosed |
| WO-1995024403-A1 | (4,4-DIFLUOROBUT-3-ENYLTHIO)-SUBSTITUTED HETEROCYCLIC OR CARBOCYCLIC RING COMPOUNDS HAVING PESTICIDAL ACTIVITY | ZENECA LIMITED (GB) | 1995-09-14 | — | — | WO | disclosed |