SCHEMBL846326

SCHEMBL846326

CC(C)C(CCCOCC1CO1)(CO[SiH3])C(C)C

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.47
ALDH1A1 P00352 4/20 0.45
TDP1 Q9NUW8 1/20 0.45
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL614618 0.80 TSHR (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL613048 0.80 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL1093578 0.78 TSHR (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL612291 0.78 SMN1; SMN2 (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL614627 0.78 SMN1; SMN2 (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL1224103 0.77 TSHR (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL15429253 0.76 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL846908 0.76 TSHR (0.56) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL845307 0.75 TSHR (0.55) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL612292 0.75 TSHR (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240401204-A1 METHOD AND COMPOSITION FOR ADJUSTING HYDROPHILICITY OF METAL USING A POLYPHENOL AND A SILANE MODIFIED NANO PARTICULATE OR AMINO ACID AMND SILICA Bulk Chemicals (US) 2024-12-05 US claimed
US-11739237-B2 Nonaqueous sol-gel for adhesion enhancement of water-sensitive materials THE BOEING COMPANY (US) 2023-08-29 US claimed
CN-115197594-A Non-aqueous sol-gel for adhesion enhancement of water sensitive materials 波音公司 2022-10-18 CN claimed
WO-2022023685-A1 COMPOSITION AND USE OF THIS COMPOSITION FOR FORMING A SOL-GEL COATING ON A METAL SURFACE ARCANE INDUSTRIES (FR) 2022-02-03 WO claimed
EP-2971230-B1 CORROSION INHIBITING SOL-GEL COMPOSITIONS PRC DESOTO INT INC (US) 2021-11-10 EP claimed
EP-3415575-B1 HYBRID COATINGS AND ASSOCIATED METHODS OF APPLICATION BOEING CO (US) 2020-10-07 EP claimed
EP-1588829-B1 Method for preparing a mold part useful for transfering a coating onto an optical substrate ESSILOR INT (FR) 2020-08-26 EP claimed
US-10370765-B2 Corrosion inhibiting sol-gel compositions PRC-DESOTO INTERNATIONAL, INC. (US) 2019-08-06 US claimed
US-20190002740-A1 NONAQUEOUS SOL-GEL FOR ADHESION ENHANCEMENT OF WATER-SENSITIVE MATERIALS THE BOEING COMPANY 2019-01-03 US claimed
US-20190002705-A1 NONAQUEOUS SOL-GEL FOR ADHESION ENHANCEMENT OF WATER-SENSITIVE MATERIALS THE BOEING COMPANY 2019-01-03 US claimed
US-20030122269-A1 Method for forming on-site a coated optical article ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2003-07-03 US claimed
US-20030116872-A1 Method for transferring from a mold a hydrophobic top coat onto an optical substrate ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2003-06-26 US claimed
US-6579472-B2 Combination of an organometallic salt, an organosilane, and a borate, phosphate, or zinc functional component. THE BOEING COMPANY 2003-06-17 US claimed
US-6540844-B1 A coupling agent provides an interface promoting adhesion between the metal surface and a polymeric protective coatings; especially for noble metals, such as gold, don't develop metal oxide surface layer CORNING INCORPORATED 2003-04-01 US claimed
US-20030024432-A1 Combination of an organometallic salt, an organosilane, and a borate, phosphate, or zinc functional component. THE BOEING COMPANY 2003-02-06 US claimed
WO-2002096628-A2 METHOD FOR FORMING ON-SITE A COATED OPTICAL ARTICLE ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2002-12-05 WO claimed
WO-2002096627-A1 METHOD FOR TRANSFERRING FROM A MOLD A HYDROPHOBIC TOP COAT ONTO AN OPTICAL SUBSTRATE. ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2002-12-05 WO claimed
US-5990333-A A THERMOSETTING POLYAMIDE OF A DICARBOXYLIC ACID AND A POLYAMINE, E.G. DIETHYLENETRIAMINE MODIFIED BY A HYDROLYZABLE REACTIVE SILANETRIOL; SIZING CELLULOSE, FIBERS AND PAPER SIZING; WET AND DRY STRENGTH OF PAPER PULP; CREPING ADHESIVE HERCULES INCORPORATED (US) 1999-11-23 US claimed
US-5789085-A WETTING WITH MIXTURE OF ALKOXYZIRONIUM AND ORGANOSILICON COMPOUND BOEING COMPANY, THE 1998-08-04 US claimed
EP-0814108-A1 Silyl-linked polyamidoamines and their preparation HERCULES INCORPORATED (US) 1997-12-29 EP claimed