SCHEMBL845307

SCHEMBL845307

CC(CCCO[SiH3])(CCCOCC1CO1)CCCOCC1CO1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.55
SMN1; SMN2 Q16637 1/20 0.53
ALDH1A1 P00352 5/20 0.50
TDP1 Q9NUW8 1/20 0.50
MAPK1 P28482 1/20 0.46
TP53 P04637 2/20 0.32
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
PPARG P37231 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL380047 0.95 TSHR (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL27958344 0.90 TSHR (0.69) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL614618 0.89 TSHR (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL18844655 0.87 ALDH1A1 (0.69) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL3592850 0.84 TSHR (0.71) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL150451 0.84 TSHR (0.78) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL1948806 0.82 TSHR (0.75) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL29055679 0.82 TSHR (0.68) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL10401328 0.82 TSHR (0.75) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL125940 0.81 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7256238-B2 Modified block copolymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2007-08-14 US claimed
EP-1199313-B1 Diene polymers and copolymers having an alkoxysilane group BRIDGESTONE CORP (JP) 2005-08-24 EP claimed
WO-2023008424-A1 RESIN COMPOSITION, METHOD FOR PRODUCING RESIN COMPOSITION, AND MOLDED BODY 旭化成株式会社 2023-02-02 WO disclosed
US-10072138-B2 Rubber composition for use in tire treads THE YOKOHAMA RUBBER CO., LTD (JP) 2018-09-11 US disclosed
US-20180022913-A1 Block Copolymer Composition, Molded Material, Resin Composition, and Molded Product ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-01-25 US disclosed
EP-3257896-A1 BLOCK COPOLYMER COMPOSITION, MOLDING MATERIAL, RESIN COMPOSITION, AND MOLDED ARTICLE Asahi Kasei Kabushiki Kaisha (JP) 2017-12-20 EP disclosed
US-9567451-B2 Rubber composition for use in tire treads THE YOKOHAMA RUBBER CO., LTD. (JP) 2017-02-14 US disclosed
US-9493638-B2 Rubber composition for tire THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-11-15 US disclosed
US-9475924-B2 Rubber composition for tire tread and pneumatic tire using the same THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-10-25 US disclosed
US-9416252-B2 Rubber composition for tire tread THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-08-16 US disclosed
US-9139721-B2 Rubber composition for tire treads THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-09-22 US disclosed
EP-0773231-B1 Diene polymers and copolymers having an alkoxysilane group BRIDGESTONE CORP (JP) 2002-07-10 EP disclosed
EP-1199313-A2 Diene polymers and copolymers having an alkoxysilane group Bridgestone Corporation (JP) 2002-04-24 EP disclosed
EP-0767179-B1 Method for producing a rubber composition BRIDGESTONE CORP (JP) 2001-06-27 EP disclosed
US-6117927-A MODIFYING TERMINAL OF A DIENE RUBBER WITH A SILANE MODIFIER HAVING A SPECIFIC FUNCTIONALITY, BRIDGESTONE CORPORATION (JP) 2000-09-12 US disclosed
EP-0661298-B1 Diene polymers and copolymers having an alkoxysilane group BRIDGESTONE CORP (JP) 1999-03-17 EP disclosed
EP-0773231-A2 Diene polymers and copolymers having an alkoxysilane group Bridgestone Corporation (JP) 1997-05-14 EP disclosed
EP-0767179-A2 Method for producing a rubber composition Bridgestone Corporation (JP) 1997-04-09 EP disclosed
US-5508333-A NONCRACKING, WEAR RESISTANCE, HYSTERESIS-FREE; TIRES BRIDGESTONE CORPORATION (JP) 1996-04-16 US disclosed
EP-0661298-A2 Diene polymers and copolymers having an alkoxysilane group BRIDGESTONE CORPORATION (JP) 1995-07-05 EP disclosed