Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2776956 | 0.86 | CSNK2A2 (0.50) | KCNN4CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL198461 | 0.83 | CSNK2A2 (0.52) | KCNN4CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL28716082 | 0.82 | CSNK2A2 (0.44) | KCNN4PDE3BPDE3ACSNK2A2CSNK2B | |
| Ethane SCHEMBL3687850 | 0.81 | CSNK2A2 (0.50) | KCNN4CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL11382359 | 0.81 | CSNK2A2 (0.50) | KCNN4CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL28837821 | 0.79 | HSP90AA1 (0.39) | KCNN4PDE3BPDE3ACSNK2A2CSNK2B | |
| SCHEMBL138361 | 0.79 | — | — | |
| SCHEMBL29943841 | 0.79 | — | — | |
| SCHEMBL28012034 | 0.78 | DPP4 (0.55) | KCNN4TAAR1HTR7CYP2D6IDO1 | |
| SCHEMBL30389980 | 0.78 | PTPRC (0.48) | KCNN4PTPRCPTPN1LMNAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934237-A1 | TETRACYCLIC COMPOUND HAVING LATERAL HALOGEN SUBSTITUENT AND LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME | CHISSO CORPORATION (JP) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998008792-A1 | TETRACYCLIC COMPOUND HAVING LATERAL HALOGEN SUBSTITUENT AND LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME | CHISSO CORPORATION (JP) | 1998-03-05 | — | — | WO | disclosed |