⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29943841 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL329693 | 0.97 | TAAR1 (0.52) | — | |
| Formaldehyde SCHEMBL27510745 | 0.95 | TAAR1 (0.50) | — | |
| Methoxymethane SCHEMBL27941731 | 0.93 | IDO1 (0.50) | — | |
| Bicarbonate SCHEMBL28309385 | 0.91 | ALDH1A1 (0.51) | — | |
| SCHEMBL30866618 | 0.79 | TAAR1 (0.62) | — | |
| SCHEMBL31675131 | 0.79 | RIPK1 (0.49) | — | |
| SCHEMBL266645 | 0.79 | RIPK1 (0.49) | — | |
| SCHEMBL31030319 | 0.79 | — | — | |
| SCHEMBL172266 | 0.79 | TAAR1 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1673 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116239594-A | 6- (imidazo [1,2-a ] pyridin-6-yl) quinazoline derivatives and uses thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-06-09 | — | — | CN | claimed |
| CN-115340992-A | Immobilized carrier and preparation method thereof, photocatalyst, preparation method and application thereof, and synthesis method of chiral alcohol | 河北工业大学 | 2022-11-15 | — | — | CN | claimed |
| EP-4021904-A1 | ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES | Idorsia Pharmaceuticals Ltd (CH) | 2022-07-06 | — | — | EP | claimed |
| WO-2021038068-A1 | ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-03-04 | — | — | WO | claimed |
| CN-107011133-A | The method that a kind of benzyl position C H keys are direct oxidation into ketone | 中国科学技术大学 | 2017-08-04 | — | — | CN | claimed |
| EP-2352723-B1 | PESTICIDAL N-ARYL- OR N-HETEROARYL PYRAZOLE CARBOXAMIDE COMPOUNDS | BAYER IP GMBH (DE) | 2016-11-23 | — | — | EP | claimed |
| CN-102317263-B | Halogen substituted compounds as pesticides | BAYER IP GMBH | 2015-04-22 | — | — | CN | claimed |
| US-20130225560-A1 | Treatment of Cognitive Disorders with Certain Alpha-7 Nicotinic Acid Receptor Agonists in Combination with Acetylcholinesterase Inhibitors | ENVIVO PHARMACEUTICALS, INC. (US) | 2013-08-29 | — | — | US | claimed |
| CN-103260619-A | Treatment of cognitive disorders using certain alpha-7 nicotinic acid receptor agonists in combination with acetylcholinesterase inhibitors | ENVIVO PHARMACEUTICALS INC | 2013-08-21 | — | — | CN | claimed |
| EP-2598135-A1 | TREATMENT OF COGNITIVE DISORDERS WITH CERTAIN ALPHA-7 NICOTINIC ACID RECEPTOR AGONISTS IN COMBINATION WITH ACETYLCHOLINESTERASE INHIBITORS | Koenig, Gerhard (US) | 2013-06-05 | — | — | EP | claimed |
| US-20100048893-A1 | Substituted arylalkanoic acid derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-02-25 | — | — | US | claimed |
| US-20100035908-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA (DK) | 2010-02-11 | — | — | US | claimed |
| CN-101611005-A | Be used as the acetophenones of the replacement of PDE4 inhibitor | LEO PHARMA AS (DK) | 2009-12-23 | — | — | CN | claimed |
| EP-2125736-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | Leo Pharma A/S (DK) | 2009-12-02 | — | — | EP | claimed |
| EP-2006271-A9 | SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2009-07-29 | — | — | EP | claimed |
| CN-101410366-A | Substituted bicyclic ring derivatives and uses thereof | ASAHI KASEI PHARMA CORP (JP) | 2009-04-15 | — | — | CN | claimed |
| US-20090062530-A1 | Substituted arylalkanoic acid derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-03-05 | — | — | US | claimed |
| US-20090054401-A1 | Substituted bicyclic derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-02-26 | — | — | US | claimed |
| EP-2006271-A2 | SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2008-12-24 | — | — | EP | claimed |
| WO-2008077404-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA A/S (DK) | 2008-07-03 | — | — | WO | claimed |