Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464139 | 1.00 | ALDH1A1 (0.39) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL15081526 | 0.87 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL3237721 | 0.87 | TSHR (0.53) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL3237734 | 0.87 | TSHR (0.53) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL13762351 | 0.87 | TSHR (0.53) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL15081437 | 0.87 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL24782805 | 0.85 | GAA (0.37) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL8084069 | 0.83 | — | — | |
| SCHEMBL9859971 | 0.83 | — | — | |
| SCHEMBL2617046 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741145-B1 | Olefin polymerization catalyst and process for producing polyolefin using the same | SUMITOMO CHEMICAL CO (JP) | 1999-12-29 | — | — | EP | disclosed |
| EP-0741145-A1 | Olefin polymerization catalyst and process for producing polyolefin using the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-11-06 | — | — | EP | disclosed |
| EP-0121838-B1 | PROCESS FOR THE PREPARATION OF 1,4-SUBSTITUTED 2-BUTENE-1,4-DIONES | BASF Aktiengesellschaft (DE) | 1986-02-26 | — | — | EP | disclosed |
| US-4513150-A | Preparation of but-2-ene-1,4-diones substituted in the 1,4-positions | BASF AKTIENGESELLSCHAFT (DE) | 1985-04-23 | — | — | US | disclosed |
| EP-0121838-A1 | Process for the preparation of 1,4-substituted 2-butene-1,4-diones | BASF Aktiengesellschaft (DE) | 1984-10-17 | — | — | EP | disclosed |
| EP-0032290-B1 | PROCESS FOR THE PREPARATION OF 1,4-DIALKYLBUT-2-ENE-1,4-DIONES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-03-14 | — | — | EP | disclosed |
| US-4340764-A | OXIDIZING 2,5-DIALKYLFURAN | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-07-20 | — | — | US | disclosed |
| US-4289526-A | FUNGICIDES, HERBICIDES, BACTERICIDES, PLANT GROWTH REGULATORS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-09-15 | — | — | US | disclosed |
| EP-0032290-A2 | Process for the preparation of 1,4-dialkylbut-2-ene-1,4-diones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-07-22 | — | — | EP | disclosed |
| US-4277469-A | FUNGICIDES, PLANT GROWTH REGULATORS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-07-07 | — | — | US | disclosed |
| EP-0023756-A2 | Triazol and imidazol derivatives; processes for their preparation, pesticidal compositions containing them and their use; preparation of intermediates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-02-11 | — | — | EP | disclosed |
| US-4246020-A | Imidazole and triazole compounds, fungicidal and plant growth regulating compositions, method of combating fungal infections in plants and method of regulating plant growth | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-01-20 | — | — | US | disclosed |
| US-4217129-A | Fungicidal and herbicidal triazole ketones | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-08-12 | — | — | US | disclosed |
| EP-0009298-A1 | Heterocyclic compounds, processes for their preparation, pesticidal compositions containing them and methods of combating pests | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-04-02 | — | — | EP | disclosed |
| EP-0002331-A2 | Imidazole and triazole compounds, fungicidal and plant growth regulating compositions, method of combating fungal infections in plants and method of regulating plant growth | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-06-13 | — | — | EP | disclosed |
| US-4130409-A | FUNGICIDE, PLANT GROWTH REGULATOR | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-12-19 | — | — | US | disclosed |