Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.48 |
| ▸ | SQLE | Q14534 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047402 | 0.90 | KMT2A (0.73) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL29056157 | 0.82 | KMT2A (0.68) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL2516095 | 0.78 | KMT2A (0.50) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL2522774 | 0.78 | KMT2A (0.52) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL26691679 | 0.78 | KMT2A (0.52) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL19454910 | 0.76 | KMT2A (0.48) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL8388835 | 0.75 | — | — | |
| SCHEMBL8600826 | 0.74 | ALDH1A1 (0.50) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL6895251 | 0.74 | KMT2A (0.48) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL8600822 | 0.74 | ALDH1A1 (0.50) | KMT2AMEN1CYP3A4ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859277-A | Silicon-containing solid support linker | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1999-01-12 | — | — | US | disclosed |