Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP12 | P39900 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | MMP14 | P50281 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP16 | P51512 | 1/20 | 0.45 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.45 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5156156 | 0.80 | PTGS1 (0.59) | PTGS1LMNAABCC4GAATSHR | |
| SCHEMBL8462611 | 0.79 | PTGS1 (0.57) | PTGS1LMNAABCC4GAATSHR | |
| SCHEMBL8464763 | 0.78 | AKR1B1 (0.57) | PTGS1LMNAABCC4GAATSHR | |
| SCHEMBL8464371 | 0.77 | EGFR (0.46) | LMNATSHRAKR1B1 | |
| SCHEMBL8460614 | 0.76 | PTGDR2 (0.41) | PTGS1LMNAHTTAKR1B1TDP1 | |
| SCHEMBL8460626 | 0.76 | SRC (0.51) | PTGS1GAATSHRAKR1B1SMN1; SMN2 | |
| SCHEMBL27717138 | 0.76 | PTGS1 (0.53) | PTGS1LMNAABCC4GAATSHR | |
| SCHEMBL27604738 | 0.76 | PTGS1 (0.57) | PTGS1LMNAABCC4GAATSHR | |
| SCHEMBL8464031 | 0.76 | KEAP1 (0.47) | LMNAHTTAKR1B1TDP1SMN1; SMN2 | |
| SCHEMBL19512828 | 0.76 | PTGS1 (0.61) | PTGS1LMNAABCC4GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |