Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | ADCY5 | O95622 | 4/20 | 0.36 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | MARS1 | P56192 | 1/20 | 0.35 |
| ▸ | IARS1 | P41252 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8467074 | 1.00 | P2RY1 (0.43) | P2RY1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8467662 | 0.93 | ADCY5 (0.36) | P2RY1ADCY5MARS1IARS1HDAC1 | |
| SCHEMBL8465925 | 0.93 | ADCY5 (0.36) | P2RY1ADCY5MARS1IARS1HDAC1 | |
| SCHEMBL8466911 | 0.90 | ADCY5 (0.37) | P2RY1ADCY5MARS1HDAC1HDAC2 | |
| SCHEMBL8466600 | 0.90 | ADCY5 (0.47) | ADCY5PDE3A | |
| SCHEMBL8465859 | 0.90 | ADCY5 (0.47) | ADCY5PDE3A | |
| SCHEMBL8464093 | 0.90 | DOT1L (0.39) | ADCY5DOT1LMARS1IARS1 | |
| SCHEMBL8464786 | 0.90 | DOT1L (0.39) | ADCY5DOT1LMARS1IARS1 | |
| SCHEMBL8467135 | 0.90 | TAAR1 (0.42) | P2RY1ADCY5MARS1IARS1 | |
| SCHEMBL8466905 | 0.89 | ADCY5 (0.36) | ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994361-A | ANTITUMOR, ANTICANCER AGENT | BIOCHEM PHARMA (CA) | 1999-11-30 | — | — | US | claimed |