SCHEMBL8464406

SCHEMBL8464406

CCC=CCCC=COC(C)=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 4/20 0.46
ALDH1A1 P00352 8/20 0.45
CYP19A1 P11511 4/20 0.45
PPARG P37231 3/20 0.45
OXER1 Q8TDS5 3/20 0.45
MAPT P10636 3/20 0.45
RXRA P19793 2/20 0.45
FFAR1 O14842 2/20 0.45
PPARA Q07869 3/20 0.44
F7 P08709 3/20 0.42
F3 P13726 3/20 0.42
ADORA3 P0DMS8 2/20 0.42
KMT2A Q03164 2/20 0.42
PPARD Q03181 2/20 0.42
NR1I2 O75469 2/20 0.42
PTGS2 P35354 2/20 0.42
PGR P06401 1/20 0.42
PDE4D Q08499 1/20 0.42
CYP3A4 P08684 2/20 0.40
ALOX15 P16050 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10337644 0.90 ALDH1A1 (0.53) PTGS1ALDH1A1CYP19A1PPARGOXER1
SCHEMBL31084290 0.90 ALDH1A1 (0.53) PTGS1ALDH1A1CYP19A1PPARGOXER1
SCHEMBL31084328 0.90 ALDH1A1 (0.53) PTGS1ALDH1A1CYP19A1PPARGOXER1
SCHEMBL6476385 0.90 ALDH1A1 (0.53) PTGS1ALDH1A1CYP19A1PPARGOXER1
SCHEMBL30879617 0.90 ALDH1A1 (0.53) PTGS1ALDH1A1CYP19A1PPARGOXER1
SCHEMBL5523640 0.90 ALDH1A1 (0.53) PTGS1ALDH1A1CYP19A1PPARGOXER1
SCHEMBL5514192 0.90 ALDH1A1 (0.53) PTGS1ALDH1A1CYP19A1PPARGOXER1
SCHEMBL6476389 0.90 ALDH1A1 (0.53) PTGS1ALDH1A1CYP19A1PPARGOXER1
SCHEMBL19333596 0.89 ALDH1A1 (0.33) PTGS1ALDH1A1ALOX15HSD17B10LMNA
SCHEMBL8466405 0.87 ALDH1A1 (0.59) PTGS1ALDH1A1CYP19A1PPARGOXER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0888274-A1 PROCESS TO PREPARE A TERMINAL ALDEHYDE DSM N.V. (NL) 1999-01-07 EP disclosed
WO-1997033854-A1 PROCESS TO PREPARE A TERMINAL ALDEHYDE DSM N.V. (NL) 1997-09-18 WO disclosed