Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 5/20 | 0.38 |
| ▸ | MMP12 | P39900 | 5/20 | 0.38 |
| ▸ | MMP13 | P45452 | 5/20 | 0.38 |
| ▸ | MMP14 | P50281 | 5/20 | 0.38 |
| ▸ | MMP9 | P14780 | 4/20 | 0.38 |
| ▸ | MMP8 | P22894 | 4/20 | 0.38 |
| ▸ | MMP16 | P51512 | 4/20 | 0.38 |
| ▸ | MMP1 | P03956 | 3/20 | 0.38 |
| ▸ | MMP3 | P08254 | 3/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6908078 | 0.78 | HSD17B10 (0.54) | ALDH1A1HSD17B10KDM4EHPGDMMP2 | |
| SCHEMBL30066779 | 0.78 | HSD17B10 (0.54) | ALDH1A1HSD17B10KDM4EHPGDMMP2 | |
| SCHEMBL8463765 | 0.78 | LCK (0.41) | ALDH1A1HSD17B10KDM4EHPGDMMP2 | |
| SCHEMBL8462410 | 0.76 | CYP1A2 (0.60) | ALDH1A1CYP1A2 | |
| SCHEMBL8464371 | 0.76 | EGFR (0.46) | ALDH1A1HPGDTSHRAKR1B1LCK | |
| SCHEMBL8462657 | 0.75 | HSD17B10 (0.59) | ALDH1A1HSD17B10KDM4EHPGDAPEX1 | |
| SCHEMBL8464031 | 0.75 | KEAP1 (0.47) | ALDH1A1HPGDSMN1; SMN2AKR1B1PTGS2 | |
| SCHEMBL8460614 | 0.75 | PTGDR2 (0.41) | ALDH1A1HSD17B10KDM4EHPGDAPEX1 | |
| SCHEMBL8460626 | 0.75 | SRC (0.51) | ALDH1A1HSD17B10KDM4EHPGDTSHR | |
| Ethylene SCHEMBL17060539 | 0.74 | HSD17B10 (0.50) | ALDH1A1HSD17B10KDM4EHPGDMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |