Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.36 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459916 | 0.89 | HSD17B10 (0.45) | HSD17B10ALDH1A1LCKFYNKDM4E | |
| SCHEMBL2988901 | 0.77 | LCK (0.56) | HSD17B10ALDH1A1LCKFYNKDM4E | |
| SCHEMBL8462610 | 0.76 | HSD17B10 (0.59) | HSD17B10ALDH1A1LCKFYNKDM4E | |
| SCHEMBL2990424 | 0.75 | LCK (0.54) | HSD17B10ALDH1A1LCKFYNKDM4E | |
| SCHEMBL27902661 | 0.75 | LCK (0.54) | HSD17B10ALDH1A1LCKFYNKDM4E | |
| SCHEMBL27487313 | 0.75 | LCK (0.54) | HSD17B10ALDH1A1LCKFYNKDM4E | |
| SCHEMBL484016 | 0.75 | LCK (0.54) | HSD17B10ALDH1A1LCKFYNKDM4E | |
| SCHEMBL5698385 | 0.75 | LCK (0.54) | HSD17B10ALDH1A1LCKFYNKDM4E | |
| SCHEMBL2917593 | 0.75 | LCK (0.54) | HSD17B10ALDH1A1LCKFYNKDM4E | |
| SCHEMBL8460400 | 0.74 | CA1 (0.46) | HSD17B10ALDH1A1KDM4EHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |