SCHEMBL2990424

SCHEMBL2990424

O=C(O)c1cc(S(=O)(=O)O)cc(C(=O)O)c1S(=O)(=O)O.[NaH]

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.54
FYN P06241 1/20 0.54
HSD17B10 Q99714 3/20 0.53
ALDH1A1 P00352 2/20 0.53
KDM4E B2RXH2 1/20 0.53
HPGD P15428 1/20 0.53
CYP2D6 P10635 1/20 0.42
S1PR3 Q99500 1/20 0.40
TSHR P16473 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
LMNA P02545 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
PHLPP2 Q6ZVD8 1/20 0.38
ING2 Q9H160 1/20 0.38
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2988901 0.98 LCK (0.56) LCKFYNHSD17B10ALDH1A1KDM4E
SCHEMBL6409409 0.82 HSD17B10 (0.49) LCKFYNHSD17B10ALDH1A1KDM4E
SCHEMBL8899334 0.81 ALDH1A1 (0.43) LCKFYNHSD17B10ALDH1A1KDM4E
SCHEMBL3442549 0.81 KDM4E (0.47) LCKFYNHSD17B10ALDH1A1KDM4E
SCHEMBL27594344 0.81 LCK (0.52) LCKFYNHSD17B10ALDH1A1KDM4E
SCHEMBL6563246 0.80 CYP2D6 (0.47) LCKFYNHSD17B10ALDH1A1KDM4E
SCHEMBL29162781 0.80 LCK (0.56) LCKFYNHSD17B10ALDH1A1KDM4E
SCHEMBL6131021 0.78 KDM4E (0.48) LCKFYNHSD17B10ALDH1A1KDM4E
SCHEMBL5698385 0.78 LCK (0.54) LCKFYNHSD17B10ALDH1A1KDM4E
SCHEMBL484016 0.78 LCK (0.54) LCKFYNHSD17B10ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7781138-B2 Low melt toners and processes thereof XEROX CORPORATION (US) 2010-08-24 US disclosed
US-20100021841-A1 LOW MELT TONERS AND PROCESSES THEREOF XEROX CORPORATION (US) 2010-01-28 US disclosed
US-7615328-B2 Low melt toners and processes thereof XEROX CORPORATION (US) 2009-11-10 US disclosed
US-20090061349-A1 LOW MELT TONERS AND PROCESSES THEREOF XEROX CORPORATION (US) 2009-03-05 US disclosed
US-7402371-B2 Low melt toners and processes thereof XEROX CORPORATION (US) 2008-07-22 US disclosed
US-20060063086-A1 Low melt toners and processes thereof XEROX CORPORATION 2006-03-23 US disclosed