Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464794 | 0.84 | GCGR (0.82) | GCGRMAPK14 | |
| SCHEMBL8464587 | 0.83 | GCGR (0.58) | GCGRMAPK14 | |
| SCHEMBL4183471 | 0.82 | GCGR (0.78) | GCGRMAPK14 | |
| SCHEMBL7642688 | 0.82 | TSHR (0.61) | — | |
| SCHEMBL4182065 | 0.77 | GCGR (0.86) | GCGRMAPK14 | |
| SCHEMBL4194651 | 0.76 | CDC7 (0.71) | GCGRMAPK14 | |
| SCHEMBL396552 | 0.76 | TSHR (0.69) | — | |
| SCHEMBL4186084 | 0.76 | CDC7 (0.68) | GCGRMAPK14 | |
| Bicarbonate SCHEMBL27449726 | 0.75 | TSHR (0.67) | — | |
| SCHEMBL21056853 | 0.74 | ALDH1A1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871444-A4 | 2,5-SUBSTITUTED ARYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO INC (US) | 1999-01-13 | — | — | EP | disclosed |
| EP-0871444-A1 | 2,5-SUBSTITUTED ARYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | Merck & Co., Inc. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997005878-A1 | 2,5-SUBSTITUTED ARYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 1997-02-20 | — | — | WO | disclosed |