Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461521 | 0.85 | TPMT (0.41) | TSHRMAPK1TPMTTP53 | |
| SCHEMBL8462406 | 0.81 | TPMT (0.36) | TSHRMAPK1TPMTTP53 | |
| SCHEMBL31534597 | 0.78 | TSHR (0.43) | TSHRMAPK1TPMTTP53 | |
| SCHEMBL8460863 | 0.74 | PTPRC (0.39) | TSHRTPMTTP53 | |
| SCHEMBL8463313 | 0.73 | MAOB (0.41) | TPMTTP53 | |
| SCHEMBL31534599 | 0.73 | KDM4E (0.41) | TSHRMAPK1TPMTTP53 | |
| SCHEMBL377395 | 0.73 | MAPK1 (0.53) | TSHRMAPK1TPMTTP53 | |
| SCHEMBL8463805 | 0.72 | CYP1A2 (0.42) | TSHRMAPK1TPMTTP53 | |
| SCHEMBL8461303 | 0.72 | TPMT (0.52) | TSHRMAPK1TPMTTP53 | |
| Hydrochloric Acid SCHEMBL11407766 | 0.71 | MAPK1 (0.52) | TSHRMAPK1TPMTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |