Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | PTPRE | P23469 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TPMT | P51580 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8463313 | 0.90 | MAOB (0.41) | PTPRCPTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL8460400 | 0.79 | CA1 (0.46) | PTPN1ALDH1A1ALOX15CYP1A2CA12 | |
| SCHEMBL8462420 | 0.77 | KEAP1 (0.45) | ALDH1A1ALOX15CYP1A2CA1CA2 | |
| SCHEMBL8463268 | 0.77 | KDM4E (0.50) | TPMTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL8461449 | 0.77 | AKR1C4 (0.52) | TPMTALDH1A1ALOX15CA1CA2 | |
| SCHEMBL8464012 | 0.77 | AKR1C3 (0.52) | PTPN1ALOX15CYP1A2CA12CA1 | |
| SCHEMBL8461303 | 0.75 | TPMT (0.52) | TPMTALDH1A1ALOX15CA12CA1 | |
| SCHEMBL8464742 | 0.74 | AKR1C3 (0.42) | — | |
| SCHEMBL8464801 | 0.74 | TSHR (0.38) | TPMTTSHRTP53 | |
| SCHEMBL8461521 | 0.74 | TPMT (0.41) | TPMTTSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |