Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.58 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20840643 | 0.88 | KMT2A (0.60) | KDM4ENPC1RAB9ASMN1; SMN2HCAR2 | |
| SCHEMBL1042215 | 0.84 | SOAT1 (0.68) | KDM4ENPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL2183707 | 0.84 | SOAT1 (0.68) | KDM4ENPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL4139016 | 0.84 | SOAT1 (0.68) | KDM4ENPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL7634493 | 0.84 | SOAT1 (0.68) | KDM4ENPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL5840193 | 0.84 | SOAT1 (0.68) | KDM4ENPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL7636178 | 0.84 | SOAT1 (0.68) | KDM4ENPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL7629650 | 0.84 | SOAT1 (0.68) | KDM4ENPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL9532980 | 0.81 | CYP2C9 (0.69) | KDM4ENPC1RAB9ASMN1; SMN2HCAR2 | |
| SCHEMBL16404495 | 0.80 | KMT2A (0.69) | KDM4ENPC1RAB9ASMN1; SMN2HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859052-A | TREATING LENTIVIRUS INFECTIONS, ESPECIALLY HUMAN IMMUNODEFICIENCY VIRUS | G. D. SEARLE & CO. (US) | 1999-01-12 | — | — | US | disclosed |