SCHEMBL8464960

SCHEMBL8464960

CCN(CC)C(=O)n1nnn(-c2c(C)cccc2Cl)c1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.39
LMNA P02545 4/20 0.37
ALDH1A1 P00352 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
GAA P10253 1/20 0.34
P2RX4 Q99571 3/20 0.34
HSD11B1 P28845 2/20 0.33
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
EPHB4 P54760 1/20 0.33
CHRNA7 P36544 2/20 0.33
POLB P06746 2/20 0.32
PTBP1 P26599 1/20 0.32
P2RX1 P51575 1/20 0.32
P2RX3 P56373 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8464962 1.00 KMT2A (0.39) KMT2ALMNAALDH1A1ALOX15TSHR
SCHEMBL9017057 0.93 KMT2A (0.36) KMT2ALMNAALDH1A1ALOX15TSHR
SCHEMBL9017056 0.93 KMT2A (0.36) KMT2ALMNAALDH1A1ALOX15TSHR
SCHEMBL6816374 0.92 P2RX4 (0.37) KMT2ALMNAALDH1A1TSHRP2RX4
SCHEMBL9017170 0.91 HPGD (0.40) KMT2ALMNAALDH1A1TSHRGAA
SCHEMBL9017174 0.91 HPGD (0.40) KMT2ALMNAALDH1A1TSHRGAA
SCHEMBL8465090 0.91 KMT2A (0.37) KMT2ALMNAALDH1A1ALOX15TSHR
SCHEMBL8465092 0.91 KMT2A (0.37) KMT2ALMNAALDH1A1ALOX15TSHR
SCHEMBL9017112 0.88 P2RX4 (0.34) KMT2ALMNATSHRGAAP2RX4
SCHEMBL9017110 0.88 P2RX4 (0.34) KMT2ALMNATSHRGAAP2RX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714602-B1 Sulphonylaminophenyluracil herbicides for paddy field BAYER AGROCHEM KK (JP) 1999-05-12 EP claimed
US-5641725-A Sulphonylaminophenyluracil herbicides for paddy field NIHON BAYER AGROCHEM K.K. (JP) 1997-06-24 US claimed
EP-0714602-A1 Sulphonylaminophenyluracil herbicides for paddy field NIHON BAYER AGROCHEM K.K. (JP) 1996-06-05 EP claimed
EP-0714602-B1 Sulphonylaminophenyluracil herbicides for paddy field BAYER AGROCHEM KK (JP) 1999-05-12 EP disclosed
US-5833733-A SOLID CORE, COATING; FUNGICIDE, HERBICIDE, NUTRIENTS; FOR RICE PADDYS NIHON BAYER AGROCHEM K.K. (JP) 1998-11-10 US disclosed
US-5641725-A Sulphonylaminophenyluracil herbicides for paddy field NIHON BAYER AGROCHEM K.K. (JP) 1997-06-24 US disclosed
EP-0578090-B1 Tetrazolinones as herbicides for use in a rice paddy BAYER AGROCHEM KK (JP) 1996-12-27 EP disclosed
EP-0714602-A1 Sulphonylaminophenyluracil herbicides for paddy field NIHON BAYER AGROCHEM K.K. (JP) 1996-06-05 EP disclosed
US-5466660-A Tetrazolinones as herbicides for use in paddy NIHON BAYER AGROCHEM K.K. (JP) 1995-11-14 US disclosed
US-5347010-A Tetrzolinone herbicides NIHON BAYER AGROCHEM K.K. (JP) 1994-09-13 US disclosed
EP-0578090-A2 Tetrazolinones as herbicides for use in a rice paddy NIHON BAYER AGROCHEM K.K. (JP) 1994-01-12 EP disclosed