Trolamine

Trolamine

SCHEMBL8464990

CCCCOC(C)(OCCCC)OP(=O)(O)O.OCCN(CCO)CCO

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 3/20 0.38
LPAR3 Q9UBY5 5/20 0.35
LPAR1 Q92633 3/20 0.35
LPAR2 Q9HBW0 3/20 0.35
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
MMP8 P22894 1/20 0.34
S1PR2 O95136 1/20 0.34
S1PR4 O95977 1/20 0.34
S1PR1 P21453 1/20 0.34
S1PR3 Q99500 1/20 0.34
FDPS P14324 2/20 0.33
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127571 0.87 SMPD1 (0.47) SMPD1LPAR3LPAR1LPAR2S1PR2
SCHEMBL11525690 0.80 LPAR3 (0.55) SMPD1LPAR3LPAR1LPAR2S1PR2
SCHEMBL14841933 0.76 LPAR3 (0.42) SMPD1LPAR3LPAR1LPAR2S1PR2
SCHEMBL14841937 0.75 SMPD1 (0.37) SMPD1LPAR3LPAR1LPAR2S1PR2
SCHEMBL10826888 0.74 LPAR3 (0.39) SMPD1LPAR3LPAR1LPAR2CYP3A4
SCHEMBL28520719 0.74 LPAR3 (0.39) SMPD1LPAR3LPAR1LPAR2FDPS
Trolamine SCHEMBL8570865 0.74 SMPD1 (0.54) SMPD1LPAR3LPAR1LPAR2S1PR2
Trolamine SCHEMBL30259699 0.74 CYP3A4 (0.47) LPAR3LPAR1LPAR2MMP1MMP2
SCHEMBL28520717 0.74 CYP3A4 (0.38) SMPD1LPAR3LPAR1LPAR2FDPS
SCHEMBL127570 0.73 CYP3A4 (0.48) SMPD1LPAR3LPAR1LPAR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024135735-A1 FOAM MOLDING COMPOSITION, FOAM-MOLDED BODY, FOAMED ELECTRIC WIRE, MANUFACTURING METHOD FOR FOAM-MOLDED BODY, MANUFACTURING METHOD FOR ELECTRIC WIRE, AND IN-VEHICLE NETWORK CABLE ダイキン工業株式会社 2024-06-27 WO disclosed
US-20230242771-A1 COMPOSITION FOR THREE-DIMENSIONAL SHAPING AND THREE-DIMENSIONAL SHAPED OBJECT DAIKIN INDUSTRIES, LTD. (JP) 2023-08-03 US disclosed
US-20230235182-A1 POWDER COMPOSITION, COATING FILM, AND THREE-DIMENSIONAL SHAPED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2023-07-27 US disclosed
EP-4215593-A1 POWDER COMPOSITION, COATING FILM, AND THREE-DIMENSIONAL SHAPED ARTICLE Daikin Industries, Ltd. (JP) 2023-07-26 EP disclosed
EP-4215568-A1 COMPOSITION FOR THREE-DIMENSIONAL SHAPING AND THREE-DIMENSIONAL SHAPED OBJECT Daikin Industries, Ltd. (JP) 2023-07-26 EP disclosed
CN-116323764-A Composition for three-dimensional modeling and three-dimensional modeling object 大金工业株式会社 2023-06-23 CN disclosed
CN-116157462-A Composition for foam molding, foam molded body, electric wire, method for producing foam molded body, and method for producing electric wire 大金工业株式会社 2023-05-23 CN disclosed
CN-116157461-A Composition for foam molding, foam molded body, electric wire, method for producing foam molded body, and method for producing electric wire 大金工业株式会社 2023-05-23 CN disclosed
US-5936048-A Method for preparing modified resins and their applications MITSUI CHEMICALS, INC. (JP) 1999-08-10 US disclosed
US-5869184-A RESIN RAW MATERIALS FOR PAINTS, ADHESIVES MITSUI TOATSU CHEMICALS, INC. (JP) 1999-02-09 US disclosed
US-5674947-A HEATING RESIN WITH FUNCTIONALIZED NORBORNENE COMPOUND IN ABSENCE OF REACTION CATALYST OR INITIATOR MITSUI TOATSU CHEMICALS, INC. (JP) 1997-10-07 US disclosed
US-5648446-A ADHESIVES, FIREPROOFING, HEAT RESISTANCE IN RESINS FOR MOLDING MATERIALS MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
US-5646240-A THERMOSETTING MOLDING COMPOSITIONS MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-08 US disclosed
US-5596039-A FLAME RETARDERS, HEAT RESISTANCE MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1997-01-21 US disclosed
US-5569726-A USEFUL IN FLAME-RETARDING, THERMAL STABILIZATION AND COMPATIBILIZATION OF RESINS AND IN THERMOSETTING MOLDING COMPOSITIONS MITSUI TOATSU CHEMICALS, INC. (JP) 1996-10-29 US disclosed
US-5545702-A THERMOSETTING RESIN COMPOSITION MITSUI TOATSU CHEMICALS, INC. (JP) 1996-08-13 US disclosed
US-5536795-A ADHESIVES AND PAINTS AND FIREPROOFING THERMOSETTING RESINS MITSUI TOATSU CHEMICALS, INC. (JP) 1996-07-16 US disclosed
EP-0698620-A1 Method for preparing modified resins and their applications MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-02-28 EP disclosed
US-5480947-A N-METHYLOL DIGUANAMINES MITSUI TOATSU CHEMICALS, INC. (JP) 1996-01-02 US disclosed
EP-0612797-A2 Modification method of resins MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-08-31 EP disclosed