Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 11/20 | 0.55 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 6/20 | 0.53 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127571 | 0.92 | SMPD1 (0.47) | LPAR3LPAR2LPAR1SMPD1S1PR2 | |
| SCHEMBL8380842 | 0.84 | LPAR3 (0.58) | LPAR3LPAR2LPAR1SMPD1LPAR5 | |
| Trolamine SCHEMBL8464990 | 0.80 | SMPD1 (0.38) | LPAR3LPAR2LPAR1SMPD1S1PR2 | |
| SCHEMBL14841933 | 0.80 | LPAR3 (0.42) | LPAR3LPAR2LPAR1SMPD1S1PR2 | |
| SCHEMBL14841937 | 0.79 | SMPD1 (0.37) | LPAR3LPAR2LPAR1SMPD1LPAR5 | |
| SCHEMBL5463517 | 0.79 | CYP3A4 (0.53) | LPAR3LPAR2LPAR1 | |
| SCHEMBL28520719 | 0.79 | LPAR3 (0.39) | LPAR3LPAR2LPAR1SMPD1 | |
| SCHEMBL10826888 | 0.79 | LPAR3 (0.39) | LPAR3LPAR2LPAR1SMPD1 | |
| SCHEMBL8050897 | 0.78 | CYP3A4 (0.47) | LPAR3LPAR2LPAR1SMPD1LPAR5 | |
| SCHEMBL28520717 | 0.78 | CYP3A4 (0.38) | LPAR3LPAR2LPAR1SMPD1GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162230-A | Method for the recovery of actinide elements from nuclear reactor waste | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1979-07-24 | — | — | US | claimed |
| US-4162230-A | Method for the recovery of actinide elements from nuclear reactor waste | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1979-07-24 | — | — | US | disclosed |
| US-4162230-A | Method for the recovery of actinide elements from nuclear reactor waste | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1979-07-24 | — | — | US | disclosed |