Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8465222 | 1.00 | CYP19A1 (0.32) | CYP19A1LMNATSHRCASP1 | |
| SCHEMBL4564982 | 0.77 | CYP19A1 (0.39) | CYP19A1 | |
| SCHEMBL28870848 | 0.71 | CYP19A1 (0.35) | CYP19A1TSHR | |
| SCHEMBL8464114 | 0.69 | — | — | |
| SCHEMBL1353098 | 0.69 | TSHR (0.40) | LMNATSHRCASP1 | |
| SCHEMBL1353096 | 0.69 | TSHR (0.40) | LMNATSHRCASP1 | |
| SCHEMBL11459056 | 0.64 | TSHR (0.36) | LMNATSHRCASP1 | |
| SCHEMBL11165834 | 0.64 | TSHR (0.36) | LMNATSHRCASP1 | |
| SCHEMBL11165836 | 0.64 | TSHR (0.36) | LMNATSHRCASP1 | |
| SCHEMBL7167365 | 0.64 | TSHR (0.43) | LMNATSHRCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766660-B1 | CYCLOHEXANONE DERIVATIVES, METHOD OF PREPARING THEM AND INTERMEDIATES USED IN THE METHOD | SCHERING AG (DE) | 1999-12-29 | — | — | EP | claimed |