Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4564982 | 0.94 | CYP19A1 (0.39) | CYP19A1 | |
| SCHEMBL30992122 | 0.77 | — | — | |
| SCHEMBL29240039 | 0.76 | CYP19A1 (0.33) | CYP19A1TSHR | |
| SCHEMBL13219645 | 0.75 | — | — | |
| SCHEMBL9878833 | 0.74 | CYP19A1 (0.32) | CYP19A1TSHR | |
| SCHEMBL7521790 | 0.72 | ALDH1A1 (0.39) | CYP19A1MAPT | |
| SCHEMBL12872930 | 0.72 | LMNA (0.32) | CYP2C9 | |
| SCHEMBL1254598 | 0.72 | MAPT (0.31) | CYP19A1MAPTCYP2C9TSHRCYP2C19 | |
| SCHEMBL30992129 | 0.71 | POLB (0.34) | CYP19A1 | |
| SCHEMBL8465218 | 0.71 | CYP19A1 (0.32) | CYP19A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476628-A | Sulfonyl cyclic alkyl amides compound as TRPA1 regulator | 豪夫迈·罗氏有限公司 | 2019-03-15 | — | — | CN | disclosed |