Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683369 | 0.87 | FFAR1 (0.40) | FFAR1FFAR4MMP2MMP12ACACB | |
| SCHEMBL7681008 | 0.84 | LMNA (0.36) | FFAR1FFAR4MMP2MMP12ACACB | |
| SCHEMBL8888060 | 0.82 | — | — | |
| Maleic Acid SCHEMBL8465327 | 0.80 | — | — | |
| SCHEMBL7680868 | 0.79 | CYP2C9 (0.39) | TP53CYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL7687493 | 0.79 | CYP2C9 (0.39) | TP53CYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL7686643 | 0.79 | CYP2C9 (0.39) | TP53CYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL7682646 | 0.79 | CYP2C9 (0.39) | TP53CYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL7686912 | 0.79 | CYP2C9 (0.39) | TP53CYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL7684939 | 0.78 | TP53 (0.40) | FFAR1FFAR4MMP2MMP12TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614631-A | ANTIINFLAMMATORY AGENTS, ANTIGROWTH AGENTS, NOOTROPIC AGENTS, BACTERICIDES, FUNGICIDES | HOECHST MARION ROUSSEL, INC. (US) | 1997-03-25 | — | — | US | claimed |
| US-5977147-A | ANTITUMOR | HOECHST MARION ROUSSEL (US) | 1999-11-02 | — | — | US | disclosed |
| US-5614631-A | ANTIINFLAMMATORY AGENTS, ANTIGROWTH AGENTS, NOOTROPIC AGENTS, BACTERICIDES, FUNGICIDES | HOECHST MARION ROUSSEL, INC. (US) | 1997-03-25 | — | — | US | disclosed |
| US-5597838-A | REDUCING INFLAMMATION AND CELL PROLIFERATION, RELIEVING MEMORY DYSFUNCTION, INHIBITING BACTERIAL AND FUNGAL GROWTH | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1997-01-28 | — | — | US | disclosed |
| US-5574164-A | 1-alkyl-,1-alkenyl-, and 1-alkynylaryl-2-amino-1,3-propanediols and related compounds | HOESCHT ROUSSEL PHARMACEUTICALS INC. (US) | 1996-11-12 | — | — | US | disclosed |
| US-5571923-A | 3-/1-DODECYL/-5-ISOXAZOLEMETHANOL INTERMEDIATE | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1996-11-05 | — | — | US | disclosed |
| US-5565584-A | CHEMICAL INTERMEDIATES | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1996-10-15 | — | — | US | disclosed |
| US-5557006-A | 1-Alkyl-, 1-alkenyl-, and 1-alkynylaryl-2-amino-1,3-propanediols and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1996-09-17 | — | — | US | disclosed |
| US-5550247-A | ANTIINFLAMMATORY AGENT, ANTITUMOR AGENT, COGNITION ACTIVATORS, BACTERICIDES, FUNGICIDES | HOECHST ROUSSEL PHARMACEUTICALS INC. (US) | 1996-08-27 | — | — | US | disclosed |
| US-5534640-A | REDUCING INFLAMMATION AND CELL PROLIFERATION, COGNITION ACTIVATORS, BACTERIOSTATS, FUNGISTATS | HOECHST ROUSSEL PHARMACEUTICALS INC. (US) | 1996-07-09 | — | — | US | disclosed |
| US-5534636-A | ANTIINFLAMMATORY AGENTS, ANTITUMOR AGENT, COGNITION ACTIVATORS,BACTERICIDES, AND FUNGICIDES | HOECHST ROUSSEL PHARMACEUTICALS INC. (US) | 1996-07-09 | — | — | US | disclosed |
| US-5519062-A | ANTIINFLAMMATORY | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1996-05-21 | — | — | US | disclosed |
| US-5488063-A | ANTIINFLAMMATORY, ANTICARACINOGENIC AGENTS; BACTERICIDES, FUNGICIDES | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1996-01-30 | — | — | US | disclosed |
| US-5488061-A | ANTIINFLAMMATORY, ANTICARACINOGENIC AGENTS; BACTERICIDES, FUNGICIDES | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1996-01-30 | — | — | US | disclosed |
| US-5360811-A | 1-alkyl-, 1-alkenyl-, and 1-alkynylaryl-2-amino-1,3-propanediols and related compounds as anti-inflammatory agents | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-11-01 | — | — | US | disclosed |