Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 13/20 | 0.54 |
| ▸ | TOP2B | Q02880 | 10/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | TOP1 | P11387 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10918381 | 0.89 | KDM4E (0.67) | TOP2ATOP2BKDM4ETOP1HPGD | |
| SCHEMBL10917492 | 0.82 | TOP2A (0.53) | TOP2ATOP2BKDM4ETOP1HPGD | |
| SCHEMBL10919879 | 0.81 | TOP2A (0.66) | TOP2ATOP2BTOP1ALDH1A1POLB | |
| SCHEMBL10918713 | 0.81 | TOP1 (0.53) | TOP2ATOP2BKDM4ETOP1HPGD | |
| SCHEMBL26193863 | 0.79 | KDM4E (0.81) | TOP2ATOP2BKDM4EHPGDHSD17B10 | |
| SCHEMBL4265220 | 0.77 | TOP2A (0.49) | TOP2ATOP2BKDM4ETOP1HPGD | |
| SCHEMBL4265670 | 0.77 | TOP2A (0.49) | TOP2ATOP2BKDM4ETOP1HPGD | |
| SCHEMBL10374439 | 0.75 | HPGD (0.64) | TOP2ATOP2BKDM4ETOP1HPGD | |
| SCHEMBL9872260 | 0.75 | KDM4E (0.62) | TOP2ATOP2BKDM4ETOP1AADAT | |
| SCHEMBL10919704 | 0.74 | TOP2A (0.47) | TOP2ATOP2BKDM4ETOP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11349589-A | — | — | None | — | — | JP | disclosed |
| JP-H11349589-A | CONDENSED RING QUINOLINECARBOXYLIC DERIVATIVE | SANKYO CO LTD | 1999-12-21 | — | — | JP | disclosed |