Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TOP1 | P11387 | 8/20 | 0.46 |
| ▸ | TOP2A | P11388 | 15/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 9/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9875030 | 0.99 | KDM4E (0.61) | KDM4EKMT2ATOP1TOP2ATOP2B | |
| SCHEMBL10918713 | 0.84 | TOP1 (0.53) | KDM4EKMT2ATOP1TOP2ATOP2B | |
| SCHEMBL21594482 | 0.79 | KDM4E (0.64) | KDM4EKMT2ATOP1TOP2ATOP2B | |
| SCHEMBL9872072 | 0.78 | KDM4E (0.63) | KDM4EKMT2ATOP1TOP2ATOP2B | |
| Bromide SCHEMBL9873492 | 0.78 | TOP1 (0.42) | KDM4EKMT2ATOP1TOP2ATOP2B | |
| Bromide SCHEMBL9873506 | 0.78 | TOP1 (0.42) | KDM4EKMT2ATOP1TOP2ATOP2B | |
| Bromide SCHEMBL9873498 | 0.78 | TOP1 (0.42) | KDM4EKMT2ATOP1TOP2ATOP2B | |
| Pazufloxacin SCHEMBL8386358 | 0.77 | KDM4E (1.00) | KDM4EKMT2ATOP2ATOP2BAADAT | |
| Pazufloxacin SCHEMBL34460 | 0.77 | KDM4E (1.00) | KDM4EKMT2ATOP2ATOP2BAADAT | |
| Pazufloxacin SCHEMBL21074686 | 0.77 | KDM4E (1.00) | KDM4EKMT2ATOP2ATOP2BAADAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | claimed |