Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5132963 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTCYP3A4KDM4EALDH1A1 | |
| SCHEMBL31529664 | 0.89 | MAPT (0.46) | SMN1; SMN2MAPTCYP3A4KDM4EALDH1A1 | |
| SCHEMBL299924 | 0.89 | MAPT (0.46) | SMN1; SMN2MAPTCYP3A4KDM4EALDH1A1 | |
| SCHEMBL2045779 | 0.80 | HDAC4 (0.50) | SMN1; SMN2MAPTCYP3A4KDM4EALDH1A1 | |
| SCHEMBL3358129 | 0.80 | HDAC4 (0.50) | SMN1; SMN2MAPTCYP3A4KDM4EALDH1A1 | |
| SCHEMBL10595471 | 0.78 | KAT6A (0.38) | SMN1; SMN2MAPTCYP3A4KDM4EALDH1A1 | |
| Pyrrolidine SCHEMBL21111261 | 0.78 | MAPT (0.37) | SMN1; SMN2MAPTCYP3A4KDM4EALDH1A1 | |
| SCHEMBL5416148 | 0.78 | GBA1 (0.38) | SMN1; SMN2MAPTCYP3A4KDM4EALDH1A1 | |
| SCHEMBL8150712 | 0.78 | GBA1 (0.38) | SMN1; SMN2MAPTCYP3A4KDM4EALDH1A1 | |
| SCHEMBL20327221 | 0.77 | GBA1 (0.43) | SMN1; SMN2MAPTCYP3A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833830-B1 | HYDROXY FUNCTIONAL ALKOXYSILANE AND ALKOXYSILANE FUNCTIONAL POLYURETHANE MADE THEREFROM | MINNESOTA MINING & MFG (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0833830-A1 | HYDROXY FUNCTIONAL ALKOXYSILANE AND ALKOXYSILANE FUNCTIONAL POLYURETHANE MADE THEREFROM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-04-08 | — | — | EP | disclosed |
| EP-0638066-B1 | Process for the preparation of a tertiary-aryl carbotiimide and alternating polycarbodiimide | DU PONT (US) | 1997-07-02 | — | — | EP | disclosed |
| US-5587502-A | MOISTURE CURABLE | MINNESOTA MINING & MANUFACTURING COMPANY (US) | 1996-12-24 | — | — | US | disclosed |
| WO-1996038453-A1 | HYDROXY FUNCTIONAL ALKOXYSILANE AND ALKOXYSILANE FUNCTIONAL POLYURETHANE MADE THEREFROM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-12-05 | — | — | WO | disclosed |
| EP-0638066-A1 | CARBODIIMIDES AND PROCESSES THEREFOR. | DU PONT (US) | 1995-02-15 | — | — | EP | disclosed |
| US-5352400-A | Carbodiimides and processes therefor | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-10-04 | — | — | US | disclosed |
| US-5349087-A | Carbodiimides and processes therefor | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-09-20 | — | — | US | disclosed |
| WO-1993022282-A2 | CARBODIIMIDES AND PROCESSES THEREFOR | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-11-11 | — | — | WO | disclosed |