Pyrrolidine

Pyrrolidine

SCHEMBL21111261

C1CCNC1.C=C(C)c1cccc(C(C)C)c1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 2/20 0.37
CYP3A4 P08684 2/20 0.37
HPGD P15428 2/20 0.37
HTT P42858 2/20 0.37
HDAC4 P56524 2/20 0.37
HDAC8 Q9BY41 2/20 0.37
MDM4 O15151 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
TP53 P04637 1/20 0.37
TYR P14679 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
CA5A P35218 1/20 0.37
MDM2 Q00987 1/20 0.37
CA9 Q16790 1/20 0.37
HDAC2 Q92769 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31529664 0.87 MAPT (0.46) MAPTSMN1; SMN2KDM4EALDH1A1CYP3A4
SCHEMBL299924 0.87 MAPT (0.46) MAPTSMN1; SMN2KDM4EALDH1A1CYP3A4
SCHEMBL5132963 0.78 SMN1; SMN2 (0.42) MAPTSMN1; SMN2KDM4EALDH1A1CYP3A4
SCHEMBL8465373 0.78 SMN1; SMN2 (0.42) MAPTSMN1; SMN2KDM4EALDH1A1CYP3A4
Pyrrolidine SCHEMBL5598380 0.76 SIGMAR1 (0.40) MAPTSMN1; SMN2ALDH1A1LMNAHSD17B10
SCHEMBL10595471 0.75 KAT6A (0.38) MAPTSMN1; SMN2KDM4EALDH1A1CYP3A4
SCHEMBL7757000 0.74 MEN1 (0.43) MAPTSMN1; SMN2KDM4EALDH1A1CYP3A4
SCHEMBL7977708 0.74 GBA1 (0.40) MAPTSMN1; SMN2KDM4EALDH1A1CYP3A4
SCHEMBL20327221 0.74 GBA1 (0.43) MAPTSMN1; SMN2KDM4EALDH1A1CYP3A4
Pyrrolidine SCHEMBL21555692 0.73 TP53 (0.42) MAPTSMN1; SMN2KDM4EALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240101744-A1 Modified Conjugated Diene-Based Polymer, Method for Preparing the Same and Rubber Composition Including the Same LG CHEM, LTD. (KR) 2024-03-28 US claimed
EP-4112657-A1 MODIFIED CONJUGATED DIENE-BASED POLYMER, PREPARATION METHOD THEREFOR, AND RUBBER COMPOSITION COMPRISING SAME LG Chem, Ltd. (KR) 2023-01-04 EP claimed
US-12018108-B2 Modified conjugated diene-based polymer LG CHEM, LTD. (KR) 2024-06-25 US disclosed
US-20240101744-A1 Modified Conjugated Diene-Based Polymer, Method for Preparing the Same and Rubber Composition Including the Same LG CHEM, LTD. (KR) 2024-03-28 US disclosed
EP-3925991-B1 MODIFIED CONJUGATED DIENE-BASED POLYMER, METHOD FOR PREPARING THE SAME AND RUBBER COMPOSITION INCLUDING THE SAME LG CHEMICAL LTD (KR) 2023-06-28 EP disclosed
US-20230159685-A1 Conjugated Diene-Based Polymer and Rubber Composition Comprising the Same LG CHEM, LTD. (KR) 2023-05-25 US disclosed
US-20230146440-A1 Oil-Extended Conjugated Diene-Based Polymer and Rubber Composition Comprising the Same LG CHEM, LTD. (KR) 2023-05-11 US disclosed
US-20230116111-A1 MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD FOR PREPARING THE SAME LG CHEM, LTD. (KR) 2023-04-13 US disclosed
EP-3689926-B1 MODIFIED CONJUGATED DIENE-BASED POLYMER AND RUBBER COMPOSITION INCLUDING THE SAME LG CHEMICAL LTD (KR) 2023-03-15 EP disclosed
US-20230051287-A1 MODIFIED CONJUGATED DIENE-BASED POLYMER, METHOD FOR PREPARING THE SAME AND RUBBER COMPOSITION COMPRISING THE SAME LG CHEM, LTD. (KR) 2023-02-16 US disclosed
US-20230038987-A1 Modified Conjugated Diene-Based Polymer and Rubber Composition Comprising the Same LG CHEM, LTD. (KR) 2023-02-09 US disclosed
EP-3567062-A1 MODIFIED CONJUGATED DIENE-BASED POLYMER AND RUBBER COMPOSITION COMPRISING SAME LG Chem, Ltd. (KR) 2019-11-13 EP disclosed
EP-3553095-A1 MODIFIED CONJUGATED DIENE POLYMER AND RUBBER COMPOSITION COMPRISING SAME LG Chem, Ltd. (KR) 2019-10-16 EP disclosed
EP-3536720-A1 MODIFIED CONJUGATED DIENE-BASED POLYMER AND RUBBER COMPOSITION COMPRISING SAME LG Chem, Ltd. (KR) 2019-09-11 EP disclosed
EP-3536721-A1 MODIFIED CONJUGATED DIENE-BASED POLYMER AND RUBBER COMPOSITION COMPRISING SAME LG Chem, Ltd. (KR) 2019-09-11 EP disclosed
EP-3536722-A1 MODIFIED CONJUGATED DIENE-BASED POLYMER AND RUBBER COMPOSITION COMPRISING SAME LG Chem, Ltd. (KR) 2019-09-11 EP disclosed
US-20190256635-A1 Method for Preparing Modified Conjugated Diene-based Polymer LG CHEM, LTD. (KR) 2019-08-22 US disclosed
US-20190233547-A1 Modified Conjugated Diene-based Polymer And Rubber Composition Including The Same LG CHEM, LTD. (KR) 2019-08-01 US disclosed
EP-3511350-A1 METHOD FOR PREPARING MODIFIED CONJUGATED DIENE-BASED POLYMER LG Chem, Ltd. (KR) 2019-07-17 EP disclosed
EP-3508508-A1 MODIFIED CONJUGATED DIENE-BASED POLYMER AND RUBBER COMPOSITION COMPRISING SAME LG Chem, Ltd. (KR) 2019-07-10 EP disclosed