Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12914594 | 0.81 | NPSR1 (0.61) | NPSR1KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL1563099 | 0.79 | NPSR1 (0.58) | NPSR1KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL900147 | 0.77 | NPSR1 (0.56) | NPSR1KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL4359334 | 0.77 | NPSR1 (0.56) | NPSR1KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL6503488 | 0.77 | NPSR1 (0.56) | NPSR1KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL264029 | 0.77 | NPSR1 (0.56) | NPSR1KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL6889531 | 0.77 | NPSR1 (0.56) | NPSR1KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL1382899 | 0.76 | MEN1 (0.67) | NPSR1KMT2AALDH1A1HTTNPC1 | |
| Hydrochloric Acid SCHEMBL27946914 | 0.76 | NPSR1 (0.54) | NPSR1KMT2AALDH1A1HTTNPC1 | |
| Hydrochloric Acid SCHEMBL9004700 | 0.76 | NPSR1 (0.54) | NPSR1KMT2AALDH1A1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939484-A | RUBBER COMPOSITION COMPRISING NATURAL RUBBER AND/OR DIENE SYNTHETIC RUBBERS, SILICA, SILANE COUPLING AGENT, I.E., A BIS(ALKOXYSILYLALKYL) POLYSULFIDE, SILICA DISPERSION; TIRE TREAD | BRIDGESTONE CORPORATION (JP) | 1999-08-17 | — | — | US | disclosed |