Sugi Predict

Sugi Predict / Compounds / SCHEMBL4359334

SCHEMBL4359334

SCHEMBL4359334

O=C(NCl)N(c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPSR1 Q6W5P4 2/20 0.56
▸ KMT2A Q03164 4/20 0.52
▸ ALDH1A1 P00352 4/20 0.52
▸ NPC1 O15118 1/20 0.52
▸ POLB P06746 1/20 0.52
▸ HTT P42858 1/20 0.52
▸ RAB9A P51151 1/20 0.52
▸ CA1 P00915 1/20 0.46
▸ CA2 P00918 1/20 0.46
▸ MEN1 O00255 3/20 0.46
▸ L3MBTL1 Q9Y468 4/20 0.45
▸ TDP1 Q9NUW8 2/20 0.45
▸ ATM Q13315 1/20 0.45
▸ TRPM8 Q7Z2W7 1/20 0.42
▸ HPGD P15428 2/20 0.40
▸ GAA P10253 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ PTGIR P43119 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27946914 0.98 NPSR1 (0.54) NPSR1KMT2AALDH1A1NPC1POLB
SCHEMBL5315495 0.89 KMT2A (0.46) NPSR1KMT2AALDH1A1NPC1POLB
SCHEMBL6243853 0.86 PTGIR (0.50) NPSR1KMT2AALDH1A1NPC1POLB
SCHEMBL2850194 0.84 NPSR1 (0.44) NPSR1KMT2AALDH1A1NPC1POLB
SCHEMBL12914594 0.81 NPSR1 (0.61) NPSR1KMT2AALDH1A1NPC1POLB
SCHEMBL2793365 0.80 ALDH1A1 (0.44) NPSR1KMT2AALDH1A1NPC1POLB
SCHEMBL2068767 0.80 NPSR1 (0.43) NPSR1KMT2AALDH1A1NPC1POLB
SCHEMBL10335782 0.79 PPARA (0.54) KMT2AALDH1A1POLBMEN1MAPT
SCHEMBL1563099 0.79 NPSR1 (0.58) NPSR1KMT2AALDH1A1NPC1POLB
SCHEMBL12914593 0.78 NPSR1 (0.52) NPSR1KMT2AALDH1A1NPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210219546-A1 METHODS OF TREATING CROP PLANTS ALTER DOMUS US LLC 2021-07-22 — — US disclosed
EP-3294052-A1 METHODS OF TREATING CROP PLANTS Agrofresh, Inc. (US) 2018-03-21 — — EP disclosed
CN-107592788-A The method for handling crop plants 阿格洛法士公司 2018-01-16 — — CN disclosed
WO-2016182995-A1 METHODS OF TREATING CROP PLANTS AGROFRESH INC (US) 2016-11-17 — — WO disclosed
CN-102802601-B Tyr-Arg dipeptides is preventing the cosmetic applications of skin sagging 赛德玛公司 2016-08-17 — — CN disclosed
US-20150282479-A1 METHODS OF TREATING CROP PLANTS AGROFRESH, INC. 2015-10-08 — — US disclosed
US-9055741-B2 Contacting crop plants with compositions ROHM AND HAAS COMPANY (US) 2015-06-16 — — US disclosed
CN-102223924-B Photoprotective composition containing an unmodified gelling starch and polyamide particles OREAL 2015-03-11 — — CN disclosed
EP-1856976-B1 Contacting crop plants with compositions ROHM & HAAS (US) 2014-09-03 — — EP disclosed
CN-101528190-B Shampoo compositions LION CORP 2013-03-20 — — CN disclosed
EP-1856976-A2 Contacting crop plants with compositions Rohm and Haas Company (US) 2007-11-21 — — EP disclosed
CN-101073320-A Contacting crop plants with compositions ROHM & HAAS (US) 2007-11-21 — — CN disclosed
US-20070265166-A1 Contacting crop plants with compositions ALTER DOMUS US LLC 2007-11-15 — — US disclosed
US-20070117720-A1 Compositions with cyclopropenes AGROFRESH, INC. 2007-05-24 — — US disclosed
EP-1787513-A2 Compositions with cyclopropenes Rohm and Haas Company (US) 2007-05-23 — — EP disclosed
CN-1965648-A Compositions with cyclopropenes ROHM & HAAS (US) 2007-05-23 — — CN disclosed
US-20060160704-A1 Plant growth regulation BASEL RICHARD M 2006-07-20 — — US disclosed
EP-1680960-A1 Plant growth regulation Rohm and Haas Company (US) 2006-07-19 — — EP disclosed
CN-1802918-A Plant growth regulation ROHM & HAAS (US) 2006-07-19 — — CN disclosed
US-5106919-A Acrylic polymers of acids or esters imidized by an N-aryl amide, sulfonamide or urea; high glass transition temperatures MOUNTEDIPE S.R.L. (IT) 1992-04-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070265166-A1 Contacting crop plants with compositions PIN1, MYB, CROCC NPSR1 4216/4885KMT2A 2081/4885ALDH1A1 3629/4885
US-20060160704-A1 Plant growth regulation MYB, SLTM, YAP1 NPSR1 1795/4885KMT2A 2987/4885ALDH1A1 4271/4885
US-20150282479-A1 METHODS OF TREATING CROP PLANTS CYCS, NOP2, CNPY3 NPSR1 3895/4885KMT2A 2541/4885ALDH1A1 3477/4885
US-20070117720-A1 Compositions with cyclopropenes MYB, OSBP, FAR1 NPSR1 3256/4885KMT2A 3786/4885ALDH1A1 2728/4885
US-20210219546-A1 METHODS OF TREATING CROP PLANTS CYCS, NOP2, CNPY3 NPSR1 3895/4885KMT2A 2541/4885ALDH1A1 3477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.