SCHEMBL846548

SCHEMBL846548

COC(=O)Cc1ccc(C(C)(C)C)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.74
SMN1; SMN2 Q16637 3/20 0.74
MAPT P10636 2/20 0.74
CYP4F2 P78329 1/20 0.59
CYP4A11 Q02928 1/20 0.59
NR1H4 Q96RI1 3/20 0.51
EPHX2 P34913 2/20 0.51
ALDH1A1 P00352 4/20 0.50
MEN1 O00255 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
KMT2A Q03164 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ESRRB O95718 1/20 0.50
ESRRG P62508 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
GAA P10253 1/20 0.49
GFER P55789 1/20 0.49
ALOX15 P16050 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38660041 0.95 LMNA (0.68) LMNASMN1; SMN2MAPTCYP4F2CYP4A11
SCHEMBL19888143 0.90 LMNA (0.63) LMNASMN1; SMN2MAPTCYP4F2CYP4A11
SCHEMBL2060889 0.89 SMN1; SMN2 (0.60) LMNASMN1; SMN2MAPTCYP4F2CYP4A11
SCHEMBL4113212 0.85 CYP4F2 (0.76) LMNASMN1; SMN2MAPTCYP4F2CYP4A11
SCHEMBL23582754 0.84 SMN1; SMN2 (0.56) LMNASMN1; SMN2MAPTCYP4F2CYP4A11
SCHEMBL5697620 0.83 SMN1; SMN2 (0.55) LMNASMN1; SMN2MAPTNR1H4EPHX2
SCHEMBL841124 0.83 CYP4F2 (0.58) LMNASMN1; SMN2MAPTCYP4F2CYP4A11
SCHEMBL1759388 0.83 CYP4F2 (0.58) LMNASMN1; SMN2MAPTCYP4F2CYP4A11
SCHEMBL10582742 0.81 SMN1; SMN2 (0.54) LMNASMN1; SMN2MAPTNR1H4EPHX2
SCHEMBL2008590 0.81 NR1H4 (0.54) LMNASMN1; SMN2MAPTCYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 467 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260013536-A1 FLAVOR COMPOSITION AND FOOD OR BEVERAGE TAKASAGO INTERNATIONAL CORPORATION (JP) 2026-01-15 US claimed
EP-4563008-A1 FRAGRANCE COMPOSITION AND FOOD OR BEVERAGE Takasago International Corporation (JP) 2025-06-04 EP claimed
CN-119584869-A Perfume composition and food and beverage 高砂香料工业株式会社 2025-03-07 CN claimed
US-20240306688-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2024-09-19 US claimed
EP-4391827-A1 METHOD OF MITIGATING OFF-ODORS Givaudan SA (CH) 2024-07-03 EP claimed
CN-117897055-A Method for reducing abnormal odor 奇华顿股份有限公司 2024-04-16 CN claimed
CN-117164593-A Pyrimidoindoles compound, preparation method and application thereof, and anti-erythroleukemia drug 贵州省天然产物研究中心 2023-12-05 CN claimed
CN-115974688-A Synthesis method of p-tert-butyl methyl phenylacetate 滕州市悟通香料有限责任公司 2023-04-18 CN claimed
WO-2023025549-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2023-03-02 WO claimed
CN-113831240-A Production method of methyl p-tert-butyl phenylacetate 滕州市天水生物科技有限公司 2021-12-24 CN claimed
JP-4739231-B2 2011-08-03 JP claimed
EP-1716159-B1 BICYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS MOMENTIVE PERFORMANCE MAT INC (US) 2011-07-13 EP claimed
US-7579495-B2 Active-releasing cyclic siloxanes MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-08-25 US claimed
US-7576170-B2 Cyclic siloxane compositions for the release of active ingredients MOMENTIVE PERFORMANCE MATERIALS (US) 2009-08-18 US claimed
EP-1697386-B1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES GEN ELECTRIC (US) 2007-10-10 EP claimed
CN-1944390-A Process for preparing P-tertiary butyl phenyl acetic ester organic compounds UNIV SHANGHAI (CN) 2007-04-11 CN claimed
EP-1697386-A1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES General Electric Company A Corporation of the State of New York (US) 2006-09-06 EP claimed
WO-2005066187-A1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES GENERAL ELECTRIC COMPANY (US) 2005-07-21 WO claimed
US-20050136021-A1 Active-releasing cyclic siloxanes MOMENTIVE PERFORMANCE MATERIALS INC. 2005-06-23 US claimed
US-20050136022-A1 Cyclic siloxane compositions for the release of active ingredients MOMENTIVE PERFORMANCE MATERIALS INC. 2005-06-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050136022-A1 Cyclic siloxane compositions for the release of active ingredients F9, RPL39, ECPAS LMNA 568/4885SMN1; SMN2 769/4885MAPT 815/4885
US-20050136021-A1 Active-releasing cyclic siloxanes F9, RPL39, ALDH16A1 LMNA 882/4885SMN1; SMN2 692/4885MAPT 1453/4885
US-20260013536-A1 FLAVOR COMPOSITION AND FOOD OR BEVERAGE EBP, FABP7, FABP2 LMNA 1010/4885SMN1; SMN2 1883/4885MAPT 2966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.