Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | BACE1 | P56817 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468231 | 0.83 | PIM1 (0.47) | MEN1KMT2ABACE1PIM1TOP2A | |
| SCHEMBL2638129 | 0.78 | KMT2A (0.49) | MEN1KMT2ABACE1LMNATSHR | |
| SCHEMBL1309432 | 0.77 | LMNA (0.71) | MEN1KMT2ABACE1LMNATSHR | |
| SCHEMBL8853168 | 0.76 | MEN1 (0.57) | MEN1KMT2ABACE1LMNATSHR | |
| SCHEMBL949738 | 0.75 | MEN1 (0.52) | MEN1KMT2ABACE1LMNATSHR | |
| SCHEMBL8467230 | 0.75 | MEN1 (0.56) | MEN1KMT2ABACE1LMNATSHR | |
| SCHEMBL3550043 | 0.74 | LMNA (0.60) | MEN1KMT2ABACE1LMNATSHR | |
| SCHEMBL1750786 | 0.74 | MKNK1 (0.49) | MEN1KMT2ABACE1LMNATSHR | |
| SCHEMBL8467788 | 0.73 | MEN1 (0.53) | MEN1KMT2ABACE1LMNATSHR | |
| SCHEMBL8852883 | 0.73 | MEN1 (0.53) | MEN1KMT2ABACE1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869184-A | RESIN RAW MATERIALS FOR PAINTS, ADHESIVES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1999-02-09 | — | — | US | disclosed |
| US-5744504-A | AMINO RESIN; THERMOSETTING MOLDING MATERIALS | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-04-28 | — | — | US | disclosed |