Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468578 | 0.90 | — | — | |
| SCHEMBL6683507 | 0.84 | CYP2D6 (0.41) | L3MBTL1UGT2B7CYP2D6TDP1KDM4E | |
| SCHEMBL18828565 | 0.80 | HCAR2 (0.52) | HCAR2L3MBTL1TDP1CA12CA1 | |
| SCHEMBL7512242 | 0.80 | HCAR2 (0.52) | HCAR2L3MBTL1TDP1CA12CA1 | |
| SCHEMBL7512241 | 0.80 | HCAR2 (0.52) | HCAR2L3MBTL1TDP1CA12CA1 | |
| SCHEMBL25249782 | 0.78 | CYP2D6 (0.46) | L3MBTL1UGT2B7CYP2D6TDP1KDM4E | |
| SCHEMBL25251873 | 0.77 | CYP2D6 (0.44) | L3MBTL1UGT2B7CYP2D6KDM4E | |
| SCHEMBL10073830 | 0.75 | HCAR2 (0.47) | HCAR2L3MBTL1TDP1CA12CA1 | |
| SCHEMBL18090625 | 0.74 | HCAR2 (0.46) | HCAR2L3MBTL1TDP1CA12CA1 | |
| SCHEMBL5789254 | 0.74 | HCAR2 (0.46) | HCAR2L3MBTL1TDP1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955627-A | Process for the preparation of cyclopropylacetylene derivatives | KURARAY CO., LTD. (JP) | 1999-09-21 | — | — | US | disclosed |