Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25249782 | 0.93 | CYP2D6 (0.46) | CYP2D6MGAMGAASIMGAM2 | |
| SCHEMBL25251873 | 0.91 | CYP2D6 (0.44) | CYP2D6MGAMGAASIMGAM2 | |
| SCHEMBL8466172 | 0.85 | CYP2D6 (0.33) | CYP2D6MGAMGAASIMGAM2 | |
| SCHEMBL7623877 | 0.85 | TSHR (0.38) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL7623909 | 0.85 | CYP2D6 (0.41) | CYP2D6MGAMGAASIMGAM2 | |
| SCHEMBL8466174 | 0.84 | HCAR2 (0.35) | CYP2D6UGT2B7L3MBTL1TDP1KDM4E | |
| SCHEMBL6682036 | 0.79 | PPM1B (0.37) | CYP2D6ALDH1A1L3MBTL1 | |
| SCHEMBL15534191 | 0.79 | MGAM (0.44) | CYP2D6MGAMGAASIMGAM2 | |
| SCHEMBL21821549 | 0.77 | MGAM (0.43) | CYP2D6MGAMGAASIMGAM2 | |
| SCHEMBL10990788 | 0.77 | UGT2B7 (0.45) | CYP2D6MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212294-A1 | Poly(3-cyclopropyl-3-hydroxypropionate) and processes for its preparation and derivatives thereof | HUBBS JOHN CLARK (US) | 2003-11-13 | — | — | US | claimed |
| US-20030208092-A1 | Poly(3-cyclopropyl-3-hydroxypropionate) and processes for its preparation and derivatives thereof | HUBBS JOHN CLARK (US) | 2003-11-06 | — | — | US | claimed |
| JP-2003518519-A | — | — | 2003-06-10 | — | — | JP | claimed |
| EP-1261657-A2 | POLY(3-CYCLOPROPYL-3-HYDROXYPROPIONATE) AND PROCESSES FOR ITS PREPARATION AND DERIVATIVES THEREOF | EASTMAN CHEMICAL COMPANY (US) | 2002-12-04 | — | — | EP | claimed |
| WO-2000068290-A2 | POLY(3-CYCLOPROPYL-3-HYDROXYPROPIONATE) AND PROCESSES FOR ITS PREPARATION AND DERIVATIVES THEREOF | EASTMAN CHEMICAL COMPANY (US) | 2000-11-16 | — | — | WO | claimed |
| CN-1200917-C | Process for preparation of cyclopropyl acethlene derivative | KURARAY CO (JP) | 2005-05-11 | — | — | CN | disclosed |
| CN-1183090-C | Method for preparation of cyclopropyl acrylic derivative | �����ɷ� | 2005-01-05 | — | — | CN | disclosed |
| EP-1261657-B1 | POLY(3-CYCLOPROPYL-3-HYDROXYPROPIONATE) AND PROCESSES FOR ITS PREPARATION AND DERIVATIVES THEREOF | EASTMAN CHEM CO (US) | 2004-11-10 | — | — | EP | disclosed |
| US-20040210030-A1 | Poly(3-cyclopropyl-3-hydroxypropionate) and processes for its preparation and derivatives thereof | HUBBS JOHN CLARK (US) | 2004-10-21 | — | — | US | disclosed |
| US-6710206-B2 | HEATING TO DEHYDROGENATE AND FORM 3-CYCLOPROPYLACRYLIC ACID; VINYLCYCLOPROPANE AND CYCLOPROPYLACETYLENE PREPARATION | EASTMAN CHEMICAL COMPANY | 2004-03-23 | — | — | US | disclosed |
| US-20030212294-A1 | Poly(3-cyclopropyl-3-hydroxypropionate) and processes for its preparation and derivatives thereof | HUBBS JOHN CLARK (US) | 2003-11-13 | — | — | US | disclosed |
| US-20030208092-A1 | Poly(3-cyclopropyl-3-hydroxypropionate) and processes for its preparation and derivatives thereof | HUBBS JOHN CLARK (US) | 2003-11-06 | — | — | US | disclosed |
| EP-0847974-B1 | Process for the preparation of cyclopropylacetylene and its derivatives | KURARAY CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| CN-1070833-C | Process for preparing cyclopropyl acetylene derivatives | KURARAY CO (JP) | 2001-09-12 | — | — | CN | disclosed |
| CN-1281840-A | Process for preparation of cyclopropyl acethlene derivative | KURARAY CO (JP) | 2001-01-31 | — | — | CN | disclosed |
| CN-1281846-A | Method for preparation of cyclopropyl acrylic derivative | KURARAY CO (JP) | 2001-01-31 | — | — | CN | disclosed |
| WO-2000068290-A2 | POLY(3-CYCLOPROPYL-3-HYDROXYPROPIONATE) AND PROCESSES FOR ITS PREPARATION AND DERIVATIVES THEREOF | EASTMAN CHEMICAL COMPANY (US) | 2000-11-16 | — | — | WO | disclosed |
| US-5955627-A | Process for the preparation of cyclopropylacetylene derivatives | KURARAY CO., LTD. (JP) | 1999-09-21 | — | — | US | disclosed |
| CN-1191856-A | Process for preparing cyclopropyl acetylene derivatives | KURARAY CO (JP) | 1998-09-02 | — | — | CN | disclosed |
| EP-0847974-A1 | Process for the preparation of cyclopropylacetylene and its derivatives | KURARAY CO., LTD. (JP) | 1998-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212294-A1 | Poly(3-cyclopropyl-3-hydroxypropionate) and processes for its preparation and derivatives thereof | HACL2, HPD, GRHPR | CYP2D6 1431/4885MGAM 592/4885GAA 1126/4885 |
| US-20030208092-A1 | Poly(3-cyclopropyl-3-hydroxypropionate) and processes for its preparation and derivatives thereof | HPD, HACL2, GRHPR | CYP2D6 1418/4885MGAM 625/4885GAA 1073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.